Cardiometabolic risk factors in people with psychotic disorders: The second Australian national survey of psychosis
Cardiometabolic risk factors in people with psychotic disorders: The second Australian national survey of psychosis
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DOI：
10.1177/0004867412453089
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发表时间：
2012-08-01
影响因子：
4.6
通讯作者：
Morgan, Vera A.
中科院分区：
文献类型：
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作者：
Galletly, Cherrie A.;Foley, Debra L.;Morgan, Vera A.
目的：为了确定澳大利亚成年人与精神病disorder.Method的心脏代谢危险因素的患病率：数据收集在第二次澳大利亚精神病调查，以人口为基础的调查年龄在18至64岁的澳大利亚人与精神病disorder的采访阶段。测量体重指数、腰围和血压。参与者被问及相关医疗条件，药物，吸烟和体育活动的诊断。分析空腹血样中的葡萄糖、高密度脂蛋白胆固醇、总胆固醇和甘油三酯。代谢综合征的患病率确定使用由国际糖尿病联盟和其他body.Results开发的协调标准：共有1087名男性（60%）和738名女性（40%）参加。他们的平均年龄为38.36岁（SD 11.16）; 773例（42%）年龄为18-34岁，1052例（58%）年龄为35-64岁。四分之三的人超重或肥胖，82%的人腹部肥胖。几乎一半是高血压。三分之二的人是目前的吸烟者，81%的人有终生吸烟史。体力活动水平非常低。大约30%的人报告了高血压或高胆固醇的诊断，20%的人知道他们患有糖尿病或高血糖，18%的人患有心血管疾病。自我报告的高血压患者中有一半正在服用抗高血压药物，约40%的高胆固醇血症或高胆固醇血症患者正在接受药物治疗。70%（N = 1286）的参与者提供了空腹血液样本。在几乎一半的参与者中发现高密度脂蛋白胆固醇和甘油三酯水平异常，近三分之一的人空腹血糖升高。超过一半的参与者（54.8%）符合代谢syndrome.Conclusions的标准：患有精神病的澳大利亚人心脏代谢危险因素的发病率很高。有一些明显的预防和治疗目标，包括肥胖症（特别是妇女）、吸烟（在男子中更为普遍）、高血压、肥胖症和久坐不动的生活方式。
Objective: To determine the prevalence of cardiometabolic risk factors in Australian adults with a psychotic disorder.Method: Data were collected during the interview phase of the second Australian survey of psychosis, a population-based survey of Australians aged 18 to 64 years with a psychotic disorder. Body mass index, waist circumference and blood pressure were measured. Participants were asked about diagnoses of relevant medical conditions, medications, smoking and physical activity. Fasting blood samples were analysed for glucose, high-density lipoprotein cholesterol, total cholesterol and triglycerides. The prevalence of metabolic syndrome was determined using the harmonized criteria developed by the International Diabetes Federation and other bodies.Results: A total of 1087 men (60%) and 738 women (40%) participated. Their mean age was 38.36 (SD 11.16) years; 773 (42%) were aged 18-34 years and 1052 (58%) 35-64 years. Three-quarters were overweight or obese and 82% had abdominal obesity. Almost half were hypertensive. Two-thirds were current smokers and 81% had a lifetime history of smoking. Levels of physical activity were very low. About 30% reported a diagnosis of hypertension or high cholesterol, 20% knew they had diabetes or high blood sugar and 18% had cardiovascular disease. Half of those with self-reported hypertension were taking antihypertensive drugs, and about 40% with hypercholesterolemia or hyperglycaemia were receiving medication for these conditions. Seventy per cent (N = 1286) of participants provided fasting blood samples. Abnormal levels of high-density lipoprotein cholesterol and triglycerides were each found in almost half of participants and almost one-third had elevated fasting glucose. More than half of participants (54.8%) met criteria for metabolic syndrome.Conclusions: Australians living with psychosis have high rates of cardiometabolic risk factors. There are a number of obvious targets for prevention and treatment, including obesity (especially in women), smoking (more prevalent in men), hypertension, hyperlipidaemia and sedentary lifestyle.