The pattern of distribution of the local axonal collaterals of Purkinje cells in the intermediate cortex of the anterior lobe and paramedian lobule of the cat cerebellum.
The pattern of distribution of the local axonal collaterals of Purkinje cells in the intermediate cortex of the anterior lobe and paramedian lobule of the cat cerebellum.
复制标题
猫小脑前叶和旁正中小叶中间皮层浦肯野细胞局部轴突侧枝的分布模式。
DOI：
10.1002/cne.902100102
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发表时间：
1982
期刊：
影响因子：
--
通讯作者：
Bishop,GA
中科院分区：
文献类型：
--
作者：
Bishop,GA
用辣根过氧化物酶对猫小脑前叶中间皮质和旁正中小叶的浦肯野细胞进行细胞内注射。对浦肯野细胞轴突在这两个皮质区的局部侧支分布进行了光镜分析。这些数据表明轴突侧支在小脑皮质的这两个区域的分布是不同的。发自前叶浦肯野细胞轴突的侧支形成一个高度分枝的、密集的串珠状神经丛，该神经丛仅限于起源细胞的直接区域。轴突分支主要位于浦肯野细胞层，但也有少数分支延伸至深至中分子层。而旁正中小叶中的浦肯野细胞发出的侧枝较少，且仅形成少数串珠链。它们延伸很长的距离，距离起源的细胞长达1毫米。在某些情况下，旁正中小叶浦肯野细胞的侧支进入皮质下白质，到达其起源叶的对侧或延伸到邻近的叶。这些数据表明，小脑皮质内回返侧支的分布模式可能并不均匀。此外，分布上的差异可能与小脑皮质这两个区域的传入和传出组织的差异有关。
Purkinje cells in the intermediate cortex of the anterior lobe and paramedian lobule of the cat cerebellum were intracellularly injected with horseradish peroxidase. Light microcopic analysis of the distribution paterns of the local collaterals arising from the axons of Purkinje cells in these two cortical areas was carried out. These data suggest that the distribution of the axon collaterals is different in these two areas of the cerebellar cortex. Collaterals arising from the axons of Purkinje cells in the anterior lobe form a highly branched, densely beaded plexus which is restricted to the immediate area of the cell of origin. The axonal ramification is located primarily along the Purkinje cell layer, although a few branches extend into the deep to middle molecular layer. In contrast, collaterals derived from Purkinje cells in the paramedian lobule branch infrequently, and give rise to only a few beaded chains. They extend for great distances, up to 1 mm from the cell of origin. In some cases, collateral branches of paramedian lobule Purkinje cells course into the subcortical white matter to the opposite side of their folium of origin or extend to adjacent folia. These data suggest that the distribution pattern of recurrent collaterals within the cerebellar cortex may not be uniform. In addition, differences in distribution may be correlated with differences in the afferent and efferent organization of the two areas in the cerebellar cortex.