Does the ultrafiltration coefficient play a key role in regulating glomerular filtration in the rat.

Does the ultrafiltration coefficient play a key role in regulating glomerular filtration in the rat.
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超滤系数在调节大鼠肾小球滤过方面是否起关键作用?

DOI:
10.1152/ajprenal.1989.256.4.f505
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发表时间:
1989
期刊:
The American journal of physiology
影响因子:
--
通讯作者:
Oken,DE
Oken,DE
中科院分区:
--
文献类型:
--
作者:
Oken,DE

文献摘要

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据报道,各种实验操作、激素和药物主要或完全通过改变滤过屏障的超滤系数(Kf)对肾小球滤过产生影响。然而,鉴于本综述中讨论的一些不确定性,Kf在肾小球功能的生理调节中确实发挥了重要作用,这一点并不确定。
Various experimental maneuvers, hormones, and pharmacological agents are reported to exert their effects on glomerular filtration largely or exclusively by changing the ultrafiltration coefficient (Kf) of the filtration barrier. In light of a number of uncertainties discussed in this review, however, it is by no means certain that the Kf actually does play this central role in the physiological regulation of glomerular function.