Photodegradation of antibiotics under simulated solar radiation: Implications for their environmental fate
Photodegradation of antibiotics under simulated solar radiation: Implications for their environmental fate
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DOI：
10.1016/j.scitotenv.2013.09.057
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发表时间：
2014-02-01
影响因子：
9.8
通讯作者：
Gardinali, Piero R.
中科院分区：
文献类型：
--
作者：
Batchu, Sudha Rani;Panditi, Venkata R.;Gardinali, Piero R.
罗红霉素、红霉素、环丙沙星和磺胺甲恶唑是环境水中经常检测到的抗生素。在不同光源照射下，在纯净水和天然水（淡水和盐水）中研究了这些有问题的抗生素的直接和间接光解作用。报告并讨论了基本的光解参数，例如摩尔吸收系数、量子产率和一级速率常数。抗生素在 254 nm 紫外线下降解最快，其次是 350 nm 和模拟太阳辐射。基质的组成（pH、溶解有机物含量、氯离子浓度）在观察到的光降解中起着重要作用。在模拟太阳辐射下，环丙沙星和磺胺甲恶唑降解相对较快，半衰期分别为0.5和1.5小时。然而，罗红霉素和红霉素、大环内酯类药物在太阳模拟下具有持久性（半衰期：2.4-10天）。使用高分辨率质谱法鉴定了辐照实验下产生的靶向抗生素的转化产物（15），并提出了降解途径。 (C) 2013 Elsevier B.V. 保留所有权利。
Roxithromycin, erythromycin, ciprofloxacin and sulfamethoxazole are frequently detected antibiotics in environmental waters. Direct and indirect photolysis of these problematic antibiotics were investigated in pure and natural waters (fresh and saltwater) under irradiation of different light sources. Fundamental photolysis parameters such as molar absorption coefficient, quantum yield and first order rate constants are reported and discussed. The antibiotics are degraded fastest under ultraviolet 254 nm, followed by 350 nm and simulated solar radiation. The composition of the matrix (pH, dissolved organic content, chloride ion concentration) played a significant role in the observed photodegradation. Under simulated solar radiation, ciprofloxacin and sulfamethoxazole degrade relatively quickly with half-lives of 0.5 and 1.5 h, respectively. However, roxithromycin and erythromycin, macrolides are persistent (half-life: 2.4-10 days) under solar simulation. The transformation products (15) of the targeted antibiotics produced under irradiation experiments were identified using high resolution mass spectrometry and degradation pathways were proposed. (C) 2013 Elsevier B.V. All rights reserved.