Computational model of the fluid dynamics in systemic-to-pulmonary shunts
Computational model of the fluid dynamics in systemic-to-pulmonary shunts
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DOI：
10.1016/s0021-9290(99)00219-5
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发表时间：
2000-05-01
影响因子：
2.4
通讯作者：
de Leval, MR
中科院分区：
文献类型：
--
作者：
Migliavacca, F;Dubini, G;de Leval, MR
体-肺分流是在体动脉循环和肺动脉循环之间建立的连接，以改善先天性心脏病患儿的肺灌注。在这个新的，外科手术创建的，心血管区的压力和流量之间的关系的知识可能有助于这些患者的临床管理，其生存是严重依赖于肺循环和体循环之间的血流分布。在这项研究中，一组三维计算模型的分流已被调查的稳态和脉动条件下，通过有限元分析。该模型用于量化分流管直径（D）、曲率、角度和脉动性对分流管压力-流量（AP-Q）关系的影响。分流器的大小主要是调节压弓关系。无名动脉直径和插入角度的影响较小。分流器的曲率导致较低的压降。惯性效应可以忽略不计。The：推导出以下简化公式：对于所研究的不同分流器几何形状（分别为直分流器和弯曲分流器），Δ P =（0.097 Q +0.521 Q（2））/D-4和Δ P =（0.096 Q +0.393 Q（2））/D-4，（C）2000 Elsevier Science Ltd.保留所有权利。
A systemic-to-pulmonary shunt is a connection created between the systemic and pulmonary arterial circulations in order to improve pulmonary perfusion in children with congenital heart diseases. Knowledge of the relationship between pressure and flow in this new, surgically created, cardiovascular district may be helpful in the clinical management of these patients, whose survival is critically dependent on the blood flow distribution between the pulmonary and systemic circulations. In this study a group of three-dimensional computational models of the shunt have been investigated under steady-state and pulsatile conditions by means of a finite element analysis. The model is used to quantify the effects of shunt diameter (D), curvature, angle, and pulsatility on the pressure-flow (AP-Q) relationship of the shunt. Size of the shunt is the main regulator of pressure-Bow relationship. Innominate arterial diameter and angles of insertion have less influence. Curvature of the shunt results in lower pressure drops. Inertial effects can be neglected. The: following simplified formulae are derived: Delta P = (0.097Q + 0.521Q(2))/D-4 and Delta P = (0.096Q + 0.393Q(2))/D-4 for the different shunt geometries investigated (straight and curved shunts, respectively), (C) 2000 Elsevier Science Ltd. All rights reserved.