Alterations of long-chain free fatty acid and magnesium concentrations in acute myocardial infarction.

Alterations of long-chain free fatty acid and magnesium concentrations in acute myocardial infarction.
复制标题

急性心肌梗塞中长链游离脂肪酸和镁浓度的变化。

DOI:
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发表时间:
1981
影响因子:
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通讯作者:
S. Shane
S. Shane
中科院分区:
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文献类型:
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作者:
E. Flink;J. Brick;S. Shane

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16例急性心肌梗死患者的血浆镁和长链游离脂肪酸(FFA)水平的变化进行了研究。在每个病人中,疼痛发作后不久,镁水平急剧下降,FFA水平急剧上升。镁和FFA值在三天内恢复正常。总镁水平的绝对下降和镁离子浓度的可能下降可能是前两天心律失常的重要因素。在各种病理和生理条件下,FFA和镁水平的同时上升和下降,为急性心肌梗死中FFA和镁浓度的不同变化提供了解释。FFA的上升似乎是镁水平的下降,这在以前是无法解释的。
Sixteen patients with acute myocardial infarction were subjects of a study of the changes in plasma magnesium and long-chain free fatty acid (FFA) levels. In each patient, there was a sharp fall of magnesium levels and a sharp rise of FFA levels shortly after onset of pain. Magnesium and FFA values returned to normal within three days. An absolute fall in total magnesium level and a probable fall in magnesium ion concentration could be important factors in arrhythmias during the first two days. The simultaneous rise in FFA and fall in magnesium levels in a variety of pathologic and physiologic conditions affords an explanation for divergent changes in FFA and magnesium concentrations in acute myocardial infarction. The FFA rise appears to be the fall in magnesium levels, which has been previously unexplained.