Understanding Release Kinetics of Calcium Alginate Microcapsules Using Drop on Demand Inkjet Printing
Understanding Release Kinetics of Calcium Alginate Microcapsules Using Drop on Demand Inkjet Printing
复制标题
使用按需喷墨打印了解海藻酸钙微胶囊的释放动力学
DOI：
10.1115/imece2009-12819
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发表时间：
2009
期刊：
影响因子：
18.9
通讯作者：
J. Sankar
中科院分区：
文献类型：
--
作者：
J. Perkins;S. Desai;B. Harrison;J. Sankar
本文研究了利用海藻酸钙微胶囊输送生物材料的药物输送。罗丹明6 G染料被封装在微胶囊中，用于使用按需喷墨打印的不同配方的水凝胶。构建实验设计以比较除了微胶囊直径之外的不同浓度的氯化钙（M）和海藻酸钠（% w/v）溶液对微胶囊的释放动力学曲线的影响。这些发现的结果为确定微胶囊的有利尺寸以及海藻酸钠和氯化钙溶液的浓度以控制微胶囊的释放行为提供了基础。
This paper investigates the use of calcium alginate microcapsules to transport biomaterials for drug delivery. Rhodamine 6G dye was encapsulated in microcapsules for different formulations of the hydrogels using drop-on-demand printing. An experimental design was constructed to compare the effect of different concentrations of calcium chloride (M) and sodium alginate (% w/v) solutions in addition to the microcapsule diameter on the release kinetics profiles of the microcapsules. The results of these findings provide a basis to identify favorable sizes of microcapsules and concentrations of sodium alginate and calcium chloride solutions for controlled release behavior of microcapsules.© 2009 ASME