Promoter prediction on a genomic scale -: The Adh experience
Promoter prediction on a genomic scale -: The Adh experience
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DOI：
10.1101/gr.10.4.539
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发表时间：
2000-04-01
期刊：
影响因子：
7
通讯作者：
Ohler, U
中科院分区：
文献类型：
--
作者：
Ohler, U
我们描述了我们的统计系统的启动子识别基因组DNA，我们参加了基因组注释评估项目（GASP 1）。我们应用了两个版本的系统：第一个使用基于区域的方法对转录起始位点识别，即内插马尔可夫链;第二个是一个混合的方法结合区域和信号内的随机段模型。我们将两个版本的结果进行了比较，并研究了基因组规模上的应用程序与我们以前在较小数据集上获得的结果相比有多好。
We describe our statistical system for promoter recognition in genomic DNA with which we took part in the Genome Annotation Assessment Project (GASP1). We applied two versions of the system: the first uses a region-based approach toward transcription start site identification, namely, interpolated Markov chains; the second was a hybrid approach combining regions and signals within a stochastic segment model. We compare the results of both versions with each other and examine how well the application on a genomic scale compares with the results we previously obtained on smaller data sets.