Brief Report: Cognitive Control Helps Explain Comorbidity Between Alcohol Use Disorder and Internalizing Disorders
Brief Report: Cognitive Control Helps Explain Comorbidity Between Alcohol Use Disorder and Internalizing Disorders
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DOI：
10.15288/jsad.2015.76.89
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发表时间：
2015-01-01
影响因子：
3.4
通讯作者：
Slutske, Wendy S.
中科院分区：
文献类型：
--
作者：
Ellingson, Jarrod M.;Richmond-Rakerd, Leah S.;Slutske, Wendy S.
目的：酒精使用和内化问题经常同时发生。认知控制与其病因有关，但没有研究测试过这种结构是否有助于解释这些疾病的共同发生。方法：共有1，313名本科生完成了认知控制，消极情绪以及酒精使用障碍（ADD），抑郁症和广泛性焦虑症症状的评估。结构方程模型研究了ADD和内化问题之间的重叠程度，解释了特定的认知控制和消极情绪的方差，以及两个结构共享的方差。结果：注意力缺失和内化障碍的症状适度相关（抑郁：r = 0.16;焦虑：r = 0.14）。认知控制特异性方差解释了ADD与抑郁和广泛性焦虑之间的显著相关性（抑郁：19%;广泛性焦虑：18%），认知控制和消极情绪的共同方差也是如此（抑郁：24%;广泛性焦虑：31%）。与以前的工作相一致，特定于负面情绪的方差也解释了AUD和内化障碍症状之间的相关性的大的和统计学上显著的比例。值得注意的是，在考虑认知控制和消极情绪后，AUD症状认可与抑郁和广泛性焦虑问题的剩余相关性在统计学上并不显著。结论：这项研究提供了新的证据，认知控制可能有助于解释AUD和内化障碍之间的重叠，同时进一步支持负面情绪对这种重叠的贡献。结果有影响的干预措施，旨在减少共病酒精使用障碍和内化障碍，以及一般的精神病理学。
Objective: Alcohol use and internalizing problems frequently co-occur. Cognitive control has been implicated in their etiology, but no studies have tested whether this construct helps explain the co-occurrence of these disorders. Method: A total of 1,313 undergraduate students completed assessments of cognitive control, negative emotionality, and symptoms of alcohol use disorder (ADD), depression, and generalized anxiety disorder. Structural equation models examined the extent to which overlap between ADD and internalizing problems was explained by variance specific to cognitive control and negative emotionality, as well as variance shared by both constructs. Results: Symptoms of ADD and internalizing disorders were modestly correlated (depression: r = .16; anxiety: r = .14). Variance specific to cognitive control explained a significant proportion of the correlation between ADD and both depression and generalized anxiety (depression: 19%; generalized anxiety: 18%), as did variance common to cognitive control and negative emotionality (depression: 24%; generalized anxiety: 31%). Consistent with previous work, variance specific to negative emotionality also explained a large and statistically significant proportion of the correlation between AUD and internalizing disorder symptoms. Of note, the residualized correlation for AUD symptom endorsement with both depression and generalized anxiety problems was not statistically significant after accounting for both cognitive control and negative emotionality. Conclusions: This study provides new evidence that cognitive control may help explain the overlap between AUD and internalizing disorders while further supporting the contribution of negative emotionality to this overlap. Results have implications for intervention efforts aimed at reducing comorbid alcohol use disorder and internalizing disorders, as well as general psychopathology.