Post-operative complications of total knee arthroplasty in patients with hypertension
Post-operative complications of total knee arthroplasty in patients with hypertension
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高血压患者全膝关节置换术后并发症
DOI：
10.1007/s00264-022-05668-8
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发表时间：
2022
影响因子：
2.7
通讯作者：
Ruofan Ma
中科院分区：
文献类型：
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作者：
Xiao;Hao Sun;Hao Li;Zhencheng Huang;Meiyi Chen;Deng Li;Zhiqing Cai;Jie Xu;Ruofan Ma
背景高血压是外科手术患者最常见的合并症之一。然而，很少有研究关注接受膝关节置换术的患者，并且大多数研究的样本量较小。本研究旨在分析接受膝关节置换术的患者中与高血压相关的术后并发症。分别分析了接受初次全膝关节置换术（pTKA）和接受无菌翻修全膝关节置换术（rTKA）的患者。进行倾向评分匹配，以减少人口统计学因素和除高血压以外的合并症对术后并发症的影响。一个多项逻辑回归，包括所有显着不同的人口统计学和合并症进行验证的结果，并评估odds ratios.ResultsA共107，981例接受pTKA和6571例接受rTKA由于机械并发症在2019年NIS数据库中确定。与非高血压组相比，高血压患者在TKA后发生急性肾功能衰竭和电解质紊乱的风险更高。进一步分析发现，低钠血症和低钾血症与高血压。结论高血压与TKA术后急性肾功能衰竭的发病率。重要的是要确定患者的急性肾功能衰竭的危险因素（除了高血压），并采取谨慎的措施，以防止急性肾功能衰竭。
BackgroundHypertension is one of the most common comorbidities among patients undergoing surgery. However, few studies have focused on patients undergoing knee arthroplasty, and most of them had small sample sizes. This study aimed to analyze post-operative complications associated with hypertension in patients who underwent knee replacement surgery.MethodsData from the 2019 National Inpatient Sample (NIS) database were used. Patients who underwent primary total knee arthroplasty (pTKA) and those who underwent aseptic revision total knee arthroplasty (rTKA) were analyzed separately. Propensity score matching was performed to reduce the effects of demographic factors and comorbidities other than hypertension on post-operative complications. A multinomial logistic regression that included all significantly different demographics and comorbidities was performed to verify the results and evaluate the odds ratios.ResultsA total of 107,981 patients who underwent pTKA and 6571 who underwent rTKA owing to mechanical complications were identified in the 2019 NIS database. Compared with the non-hypertension group, patients with hypertension had a higher risk of developing acute renal failure and electrolyte disorders after TKA. Further analysis revealed that hyponatraemia and hypokalaemia were associated with hypertension.ConclusionsHypertension was associated with the incidence of acute renal failure after TKA. It is important to identify patients with risk factors for acute renal failure (in addition to hypertension) and take careful measures to prevent acute renal failure in them.
DOI：
10.1016/s0140-6736(21)01330-1
发表时间：
2021-09-11
期刊：
Lancet (London, England)
影响因子：
--
作者：
NCD Risk Factor Collaboration (NCD-RisC)
通讯作者：
NCD Risk Factor Collaboration (NCD-RisC)