Engineering Iron Oxide Hollow Nanospheres to Enhance Antimicrobial Property: Understanding the Cytotoxic Origin in Organic Rich Environment
Engineering Iron Oxide Hollow Nanospheres to Enhance Antimicrobial Property: Understanding the Cytotoxic Origin in Organic Rich Environment
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DOI：
10.1002/adfm.201601459
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发表时间：
2016-08-09
影响因子：
19
通讯作者：
Yu, Chengzhong
中科院分区：
文献类型：
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作者：
Nor, Yusilawati Ahmad;Zhou, Liang;Yu, Chengzhong
工程磁性氧化铁纳米颗粒具有令人惊讶的高抗菌活性和对哺乳动物细胞株的极好的安全性。用硬模板法制备了赤铁矿中空纳米球(HNSS)，用H-2还原赤铁矿中空纳米球可得到磁铁矿HNSS。用赤铁矿HNSS和常规磁铁矿(直径为C-磁铁矿)评价了磁铁矿HNSS对革兰氏阴性菌(大肠杆菌)和革兰氏阳性菌(表皮葡萄球菌)的抑菌活性
Engineered magnetic iron oxide nanoparticles with surprisingly high antimicrobial activity and excellent safety profiles to mammalian cell lines have been developed. Hematite hollow nanospheres (HNSs) are prepared by a facile hard templating method; reduction of hematite HNSs by H-2 leads to magnetite HNSs. The antimicrobial activity of magnetite HNSs towards Gram negative (Escherichia coli) and Gram positive (Staphylococcus epidermidis) bacteria is evaluated against hematite HNSs and conventional magnetite (C-magnetite; diameter