Early adolescent psychopathology as a predictor of alcohol use disorders by young adulthood
Early adolescent psychopathology as a predictor of alcohol use disorders by young adulthood
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DOI：
10.1016/j.drugalcdep.2006.12.014
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发表时间：
2007-04-01
影响因子：
4.2
通讯作者：
Stouthamer-Loeber, Magda
中科院分区：
文献类型：
--
作者：
Pardini, Dustin;White, Helene Raskin;Stouthamer-Loeber, Magda
很少有前瞻性研究探讨青少年早期品行障碍 (CD) 症状与青年期酒精使用障碍 (AUD) 发展之间的关系。其他形式的青少年精神病理学（即注意力缺陷多动障碍、抑郁、焦虑/退缩）对 AUD 发展的相对贡献也仍然知之甚少。有人认为，行为障碍症状与其他形式的精神病理学的同时出现可能会在预测以后的饮酒问题方面产生协同作用。当前的研究使用来自匹兹堡青年研究 (PYS) 最年长样本的 506 名男孩的数据来探讨这些问题。与之前的研究一致，早期行为障碍症状是 AUD 症状增加和成年早期酒精依赖诊断的一致预测因素。相比之下，焦虑/戒断程度高的青春期男孩的 AUD 症状水平较低，并且在成年初期出现酒精依赖的可能性较小。青春期早期抑郁症的增加与成年早期较高的 AUD 症状以及酗酒和依赖诊断有关，但仅限于行为障碍症状严重的男孩。在控制同时发生的精神病理学后，没有发现证据表明注意力缺陷多动障碍症状与 AUD 症状或诊断之间存在关系。 (c) 2007 Elsevier Ireland Ltd. 保留所有权利。
Few prospective studies have examined the relation between early adolescent conduct disorder (CD) symptoms and the development of alcohol use disorders (AUD) by young adulthood. The relative contribution of other forms of adolescent psychopathology (i.e., attention-deficit hyperactivity disorder, depression, anxiety/withdrawal) to the development of AUD also remains poorly understood. There is some suggestion that the co-occurrence of conduct disorder symptoms with other forms of psychopathology may interact synergistically in predicting later alcohol use problems. The current study explores these issues using data on 506 boys from the oldest sample of the Pittsburgh Youth Study (PYS). Consistent with prior research, early conduct disorder symptoms emerged as a consistent predictor of increased AUD symptoms and an alcohol dependence diagnosis by young adulthood. In contrast, adolescent boys with high levels of anxiety/withdrawal had lower levels of AUD symptoms and were less likely to develop alcohol dependence by young adulthood. Increased depression in early adolescence was associated with higher AUD symptoms and alcohol abuse and dependence diagnoses by young adulthood, but only for boys with high levels of conduct disorder symptoms. No evidence was found for a relation between attention-deficit hyperactivity disorder symptoms and AUD symptoms or diagnoses after controlling for co-occurring psychopathology. (c) 2007 Elsevier Ireland Ltd. All rights reserved.