Primary tumor volume should be included in the TNM staging system of nasopharyngeal carcinoma

Primary tumor volume should be included in the TNM staging system of nasopharyngeal carcinoma
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原发肿瘤体积应纳入鼻咽癌TNM分期系统

DOI:
10.1016/j.mehy.2014.01.032
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发表时间:
2014-04-01
期刊:
影响因子:
4.7
通讯作者:
Hu, Guoqing
Hu, Guoqing
中科院分区:
医学4区
文献类型:
--
作者:
Liu, Dongbo;Long, Guoxian;Hu, Guoqing

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TNM staging system based on anatomic location, cranial nerve and conventional radiation therapy is currently the widely used classification for nasopharyngeal carcinoma (NPC). However, the T classification in separation of primary tumor volume fail to predict the radiosensitivity of primary tumor. And with the advent of intensity-modulated radiation therapy (IMRT), increasing studies show the significance of the primary tumor volume on the treatment outcome of NPC patients and primary tumor volume significantly improve the prognostic validity of T classification in NPC. What's more, the current T staging system has limitations to provide appropriate treatment for different subgroup NPC patients. Therefore, we propose that primary tumor volume should be included in the TNM staging system of nasopharyngeal carcinoma to guide our clinical decision. (C) 2014 Elsevier Ltd. All rights reserved.