The Relationship between Pollen Count Levels and Prevalence of Japanese Cedar Pollinosis in Northeast Japan
The Relationship between Pollen Count Levels and Prevalence of Japanese Cedar Pollinosis in Northeast Japan
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DOI：
10.2332/allergolint.12-oa-0526
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发表时间：
2013-09-01
影响因子：
6.8
通讯作者：
Ishikawa, Kazuo
中科院分区：
文献类型：
--
作者：
Honda, Kohei;Saito, Hidekazu;Ishikawa, Kazuo
背景：日本儿童中日本柳杉（JC）花粉症的患病率正在上升。然而，很少有研究报道花粉计数水平与花粉症患病率之间的关系。为了评估日本柳杉花粉计数水平与儿童花粉症患病率之间的关系，我们在日本东北部秋田的两个地区对日本柳杉花粉的致敏情况和症状发展进行了调查，这两个地区对日本柳杉花粉的暴露水平存在差异。
方法：研究人群包括2005 - 2006年来自秋田沿海和山区的339名小学生（10 - 11岁）。学生家长填写了一份关于过敏性鼻炎症状的问卷。采集血液样本以确定针对五种常见气传过敏原的特异性IgE抗体。
结果：1996 - 2006年，山区的平均花粉计数是沿海地区的两倍。两个地区螨虫所致的鼻过敏症状患病率和致敏率几乎相同。另一方面，山区日本柳杉花粉所致的鼻过敏症状患病率和致敏率明显高于沿海地区。对日本柳杉花粉致敏的儿童中症状出现的比率在两个地区几乎相同。
结论：这些结果表明，花粉计数水平可能与日本柳杉花粉症的致敏率相关，但可能不会影响日本东北部致敏儿童的发病比率。
Background: The prevalence of Japanese cedar (JC) pollinosis in Japanese children is increasing. However, few studies have reported the relationship between pollen count levels and the prevalence of pollinosis. To evaluate the relationship between JC pollen count levels and the prevalence of pollinosis in children, we investigated the sensitization and development of symptoms for JC pollen in two areas of Akita in northeast Japan with contrasting levels of exposure to JC pollen.Methods: The study population consisted of 339 elementary school students (10-11 years of age) from the coastal and mountainous areas of Akita in 2005-2006. A questionnaire about symptoms of allergic rhinitis was filled out by the students' parents. A blood sample was taken to determine specific IgE antibodies against five common aeroallergens.Results: The mean pollen count in the mountainous areas was two times higher than that in the coastal areas in 1996-2006. The prevalence rates of nasal allergy symptoms and sensitization for mites were almost the same in both areas. On the other hand, the rates of nasal allergy symptoms and sensitization for JC pollen were significantly higher in the mountainous areas than in the coastal areas. The rate of the development of symptoms among children sensitized for JC pollen was almost the same in both areas.Conclusions: These results suggest that pollen count levels may correlate with the rate of sensitization for JC pollinosis, but may not affect the rate of onset among sensitized children in northeast Japan.