Evaluation of prevalence and risk factors for methicillin-resistant Staphylococcus aureus colonization in veterinary personnel attending an international equine veterinary conference
Evaluation of prevalence and risk factors for methicillin-resistant Staphylococcus aureus colonization in veterinary personnel attending an international equine veterinary conference
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DOI：
10.1016/j.vetmic.2007.11.031
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发表时间：
2008-06-22
影响因子：
3.3
通讯作者：
Weese, J. Scott
中科院分区：
文献类型：
--
作者：
Anderson, Maureen E. C.;Lefebvre, Sandra L.;Weese, J. Scott
耐甲氧西林金黄色葡萄球菌（MRSA）的感染和定植现在越来越多地报告在动物和与动物一起工作的人，包括马和马的工作人员。本研究的目的是评估参加国际马兽医会议的兽医人员中MRSA定植的患病率，并确定该组中MRSA定植的危险因素。在会议上招募志愿者，提供一个鼻拭子，并完成一份关于与人类卫生保健系统接触、与马接触和个人手部卫生的问卷。在26/257（10.1%）的研究参与者中发现MRSA定植。多变量分析显示，MRSA定植的风险增加与过去一年中被诊断为MRSA定植或感染的患者相关（比值比[OR] 8.41，95%可信区间[CI] 1.51-49.92，P = 0.015; OR 3.27，95%CI 1.05-10.11，P = 0.039），而感染病例之间洗手（OR 0.27，95% CI 0.11-0.72，P = 0.009）和农场间洗手（OR 0.35，95% CI 0.14-0.98，P = 0.047）具有保护作用。与其他针对一般人群的研究相比，本研究中发现的马兽医人员中MRSA定植的患病率较高。这些数据支持先前的建议，即马兽医人员与MRSA定植的风险增加。这是第一项证明手卫生习惯与兽医学可测量临床结果之间存在统计学显著相关性的研究。(C)2007 Elsevier B. V.保留所有权利。
Infection and colonization with methicillin-resistant Staphylococcus aureus (MRSA) are now increasingly being reported in animals and people who work with animals, including horses and horse personnel. The objectives of this study were to evaluate the prevalence of MRSA colonization in veterinary personnel attending an international equine veterinary conference, and to identify risk factors for MRSA colonization in this group. Volunteers were recruited at the conference to provide a single nasal swab and complete a questionnaire regarding contact with the human health care system, contact with horses, and personal hand hygiene. Colonization with MRSA was found in 26/257 (10.1%) of study participants. Multivariable analysis showed an increased risk of MRSA colonization associated with having been diagnosed with or having treated a patient diagnosed with MRSA colonization or infection in the last year (odds ratio [OR] 8.41, 95% confidence interval [CI] 1.51-49.92, P = 0.015; OR 3.27, 95% CI 1.05-10.11, P = 0.039, respectively), whereas hand washing between infectious cases (OR 0.27, 95% CI 0.11-0.72, P = 0.009) and hand washing between farms (OR 0.35, 95% CI 0.14-0.98, P = 0.047) were protective. The prevalence of MRSA colonization among equine veterinary personnel found in this study was high compared to that of other studies of the general population. These data support previous suggestions that equine veterinary personnel are at increased risk of colonization with MRSA. This is the first study to demonstrate a statistically significant association between hand hygiene practices and a measurable clinical outcome in veterinary medicine. (C) 2007 Elsevier B.V. All rights reserved.