The calcified lung nodule: What does it mean?

The calcified lung nodule: What does it mean?
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DOI:
10.4103/1817-1737.62469
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发表时间:
2010-04
影响因子:
2.3
通讯作者:
Koteyar SS
Koteyar SS
中科院分区:
医学4区
文献类型:
--
作者:
Khan AN;Al-Jahdali HH;Allen CM;Irion KL;Al Ghanem S;Koteyar SS

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这篇综述的目的是提出一个图文并茂的文章,强调各种模式的钙化在肺结节(PN),以帮助诊断和讨论的鉴别诊断和发病机制,它是已知的。PN的影像学评价基于临床病史、结节的大小、分布和大体外观以及获得组织诊断的可行性。影像学检查有助于PN的治疗,不仅要努力识别具有高生存率的小恶性肿瘤,而且要使良性PN患者免于接受不必要的手术。审查强调如何实现这些目标。良性病变最可靠的影像学特征之一是钙化的良性模式和定期随访的计算机断层扫描显示无生长2年。PN中的钙化通常被认为是可能的良性疾病的指标。然而,正如我们在这里所展示的,以PN中的钙化作为判断良性性质的标准是错误的,可能会产生误导。钙化病变的鉴别诊断包括钙化肉芽肿、错构瘤、类癌、骨肉瘤、软骨肉瘤和肺转移瘤或原发性支气管癌等。我们描述和说明不同的模式钙化所看到的PN的成像。
The aim of this review is to present a pictorial essay emphasizing the various patterns of calcification in pulmonary nodules (PN) to aid diagnosis and to discuss the differential diagnosis and the pathogenesis where it is known. The imaging evaluation of PN is based on clinical history, size, distribution and the gross appearance of the nodule as well as feasibility of obtaining a tissue diagnosis. Imaging is instrumental in the management of PN and one should strive not only to identify small malignant tumors with high survival rates but to spare patients with benign PN from undergoing unnecessary surgery. The review emphasizes how to achieve these goals. One of the most reliable imaging features of a benign lesion is a benign pattern of calcification and periodic follow-up with computed tomography showing no growth for 2 years. Calcification in PN is generally considered as a pointer toward a possible benign disease. However, as we show here, calcification in PN as a criterion to determine benign nature is fallacious and can be misleading. The differential considerations of a calcified lesion include calcified granuloma, hamartoma, carcinoid, osteosarcoma, chondrosarcoma and lung metastases or a primary bronchogenic carcinoma among others. We describe and illustrate different patterns of calcification as seen in PN on imaging.
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