Waterpipe Tobacco and Cigarette Smoking Direct Comparison of Toxicant Exposure
Waterpipe Tobacco and Cigarette Smoking Direct Comparison of Toxicant Exposure
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DOI：
10.1016/j.amepre.2009.07.014
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发表时间：
2009-12-01
影响因子：
5.5
通讯作者：
Shihadeh, Alan
中科院分区：
文献类型：
--
作者：
Eissenberg, Thomas;Shihadeh, Alan
背景：水烟（水烟、水烟）吸烟已在全世界蔓延。许多水烟吸烟者认为，相对于香烟，水烟的烟雾毒性水平较低，健康风险也较小。为了使医生可信地解决这些问题，必须直接比较水烟的使用和吸烟。目的：本研究的目的是对与水烟烟草和吸烟相关的毒物暴露进行首次受控、直接的实验室比较。方法：参与者（N = 31；M = 21.4 岁，SD = 2.3）报告每月水烟使用情况（M = 5.2 使用/月， SD=4.0）和每周吸烟（M=9.9支/天，SD=6.4）完成了一项交叉研究，其中他们每人吸一根水烟最多45分钟，或一支香烟。结果测量包括疗程结束后 5 分钟的呼出气体一氧化碳 (CO)、血液碳氧血红蛋白 (COHb)、血浆尼古丁、心率和抽吸地形。数据收集于 2008-2009 年，并于 2009 年进行分析。 结果：平均而言，使用水烟时 CO 增加 23.9 ppm (SD=19.8)，吸烟时 CO 增加 2.7 ppm (SD=1.8)，而水烟 COHb 峰值水平 (M=3.9%，SD=2.5) 是吸烟时观察到的水平 (M=1.3%，SD=0.5； p 的
Background: Waterpipe (hookah, shisha) tobacco smoking has spread worldwide. Many waterpipe smokers believe that, relative to cigarettes, waterpipes are associated with lower smoke toxicant levels and fewer health risks. For physicians to address these beliefs credibly, waterpipe use and cigarette smoking must be compared directly.Purpose: The purpose of this study is to provide the first controlled, direct laboratory comparison of the toxicant exposure associated with waterpipe tobacco and cigarette smoking.Methods: Participants (N=31; M=21.4 years, SD=2.3) reporting monthly waterpipe use (M=5.2 uses/month, SD=4.0) and weekly cigarette smoking (M=9.9 cigarettes/day, SD=6.4) completed a crossover study in which they each smoked a waterpipe for a maximum of 45 minutes, or a single cigarette. Outcome measures included expired-air carbon monoxide (CO) 5 minutes after session's end, and blood carboxyhemoglobin (COHb), plasma nicotine, heart rate, and puff topography. Data were collected in 2008-2009 and analyzed in 2009.Results: On average, CO increased by 23.9 ppm for waterpipe use (SD=19.8) and 2.7 ppm for cigarette smoking (SD=1.8), while peak waterpipe COHb levels (M=3.9%, SD=2.5) were three times those observed for cigarette smoking (M=1.3%, SD=0.5; p's