Mindfulness Meditation for Chronic Pain: Systematic Review and Meta-analysis.
Mindfulness Meditation for Chronic Pain: Systematic Review and Meta-analysis.
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DOI：
10.1007/s12160-016-9844-2
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发表时间：
2017-04
期刊：
影响因子：
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通讯作者：
Maglione MA
中科院分区：
文献类型：
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作者：
Hilton L;Hempel S;Ewing BA;Apaydin E;Xenakis L;Newberry S;Colaiaco B;Maher AR;Shanman RM;Sorbero ME;Maglione MA
慢性疼痛患者越来越多地通过正念冥想寻求治疗。本研究旨在综合正念冥想干预治疗成人慢性疼痛的有效性和安全性的证据。我们使用Hartung-Knapp-Sidik-Jonkman随机效应模型方法对随机对照试验（RCT）进行了系统评价。使用GRADE方法评估证据质量。结果包括疼痛、抑郁、生活质量和镇痛药的使用。38项RCT符合入选标准; 7项报告了安全性。我们发现低质量的证据表明，与30项随机对照试验中的所有类型的对照相比，正念冥想与疼痛的小幅减少有关。对抑郁症状和生活质量也有统计学意义的影响。虽然正念冥想可以改善疼痛和抑郁症状以及生活质量，但还需要更多精心设计的、严格的、大规模的随机对照试验来确定正念冥想对慢性疼痛的疗效。本文的在线版本（doi：10.1007/s12160-016-9844-2）包含补充材料，可供授权用户使用。
Chronic pain patients increasingly seek treatment through mindfulness meditation. This study aims to synthesize evidence on efficacy and safety of mindfulness meditation interventions for the treatment of chronic pain in adults. We conducted a systematic review on randomized controlled trials (RCTs) with meta-analyses using the Hartung-Knapp-Sidik-Jonkman method for random-effects models. Quality of evidence was assessed using the GRADE approach. Outcomes included pain, depression, quality of life, and analgesic use. Thirty-eight RCTs met inclusion criteria; seven reported on safety. We found low-quality evidence that mindfulness meditation is associated with a small decrease in pain compared with all types of controls in 30 RCTs. Statistically significant effects were also found for depression symptoms and quality of life. While mindfulness meditation improves pain and depression symptoms and quality of life, additional well-designed, rigorous, and large-scale RCTs are needed to decisively provide estimates of the efficacy of mindfulness meditation for chronic pain. The online version of this article (doi:10.1007/s12160-016-9844-2) contains supplementary material, which is available to authorized users.