Deep learning-based muscle segmentation and quantification at abdominal CT: application to a longitudinal adult screening cohort for sarcopenia assessment

Deep learning-based muscle segmentation and quantification at abdominal CT: application to a longitudinal adult screening cohort for sarcopenia assessment
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DOI:
10.1259/bjr.20190327
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发表时间:
2019-01-01
影响因子:
2.6
通讯作者:
Summers, Ronald M.
Summers, Ronald M.
中科院分区:
医学3区
文献类型:
--
作者:
Graffy, Peter M.;Liu, Jiamin;Summers, Ronald M.

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目的:调查一个全自动腹部CT为基础的肌肉工具在一个大的成人screeningpopulation.Methods:一个全自动验证的肌肉分割算法应用于9310非对比CT扫描,包括一个主要的筛选队列的8037个连续的无症状的成年人(平均年龄,57.1 +/- 7.8岁; 3555 M/4482 F)。在1171个个体的子集中进行了连续的随访扫描(平均间隔,5.1年),肌肉组织横截面积和衰减结果:男性两种肌肉面积的平均值均显著高于男性(190.6 ± 33.6 vs 133.3 ± 24.1 cm(2),p
Objective: To investigate a fully automated abdominal CT-based muscle tool in a large adult screening population.Methods: A fully automated validated muscle segmentation algorithm was applied to 9310 non-contrast CT scans, including a primary screening cohort of 8037 consecutive asymptomatic adults (mean age, 57.1 +/- 7.8 years; 3555M/4482F). Sequential follow-up scans were available in a subset of 1171 individuals (mean interval, 5.1 years), Muscle tissue cross-sectional area and attenuation (Hounsfield unit, HU) at the L3 level were assessed, including change over time.Results: Mean values were significantly higher in males for both muscle area (190.6 +/- 33.6 vs 133.3 +/- 24.1 cm(2), p