Signet-ring Cell (Mucin-Producing) Adenocarcinomas of Minor Salivary Glands
Signet-ring Cell (Mucin-Producing) Adenocarcinomas of Minor Salivary Glands
复制标题
小唾液腺印戒细胞（产生粘蛋白）腺癌
DOI：
10.1097/00000478-200401000-00010
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发表时间：
2004
期刊：
影响因子：
--
通讯作者：
P. Freedman
中科院分区：
文献类型：
--
作者：
J. Ghannoum;P. Freedman
我们报告7例小涎腺癌的特点是显着存在含粘蛋白的印戒细胞。这些肿瘤在显微镜下的外观是独特的，并显示出在任何其他类型的唾液腺恶性肿瘤中未见的特征。它们通常表现为狭窄的平行链，随机分散的小巢或单独浸润细胞的侵入性生长。不存在实性、筛状或靶样区域以及乳头状成分。导管分化是最小的，只在4例中看到。不同区域的细胞性程度不同。肿瘤在细胞学上是温和的。我们认为，这些肿瘤代表了一个独特的亚组口腔内小涎腺癌。
We report seven cases of minor salivary gland carcinomas characterized by the marked presence of mucin-containing signet-ring cells. These tumors were distinctive in their microscopic appearance and displayed features not seen in any other type of salivary gland malignancy. They typically exhibited invasive growth by narrow parallel strands, randomly scattered small nests, or individually infiltrating cells. Solid, cribriform, or targetoid areas were absent, as well as papillary components. Ductal differentiation was minimal, and seen in only four cases. Degrees of cellularity varied from one area to another. The tumors were cytologically bland. We think that these tumors represent a unique subset of intraoral minor salivary gland carcinomas.