Antimicrobial resistance in intensive care units
Antimicrobial resistance in intensive care units
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DOI：
10.1016/s0272-5231(05)70143-x
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发表时间：
1999-06-01
影响因子：
5.7
通讯作者：
Gaynes, RP
中科院分区：
文献类型：
--
作者：
Fridkin, SK;Gaynes, RP
重症监护病房（ICU）环境的独特性质使医院的这一部分成为许多抗微生物药物耐药性病原体出现和传播的焦点。耐药细菌在患者之间有充分的交叉传播机会，患者通常暴露于广谱抗微生物药物。与ICU患者院内感染相关的大多数病原体的耐药率增加，并且ICU患者的耐药率几乎普遍高于非ICU患者。然而，通过改进现有感染控制措施（即患者隔离、洗手、使用手套和适当使用长袍）以及对抗菌素使用情况进行系统审查，有许多机会可以防止这些耐药病原体的出现和传播。
The unique nature of the intensive care unit (ICU) environment makes this part of the hospital a focus for the emergence and spread of many antimicrobial-resistant pathogens. There are ample opportunities for the cross-transmission of resistant bacteria from patient to patient, and patients are commonly exposed to broad-spectrum antimicrobial agents. Rates of resistance have increased for most pathogens associated with nosocomial infections among ICU patients, and rates are almost universally higher among ICU patients compared with non-ICU patients. There are many opportunities, however, to prevent the emergence and spread of these resistant pathogens through improved use of established infection control measures (i.e., patient isolation, hand washing, glove use, and appropriate gown use), and implementation of a systematic review of antimicrobial use.