EFFECT OF CHRONIC STRESS ASSOCIATED WITH UNEMPLOYMENT ON SALIVARY COLTISOL - OVERALL CORTISOL-LEVELS, DIURNAL RHYTHM, AND ACUTE STRESS REACTIVITY

EFFECT OF CHRONIC STRESS ASSOCIATED WITH UNEMPLOYMENT ON SALIVARY COLTISOL - OVERALL CORTISOL-LEVELS, DIURNAL RHYTHM, AND ACUTE STRESS REACTIVITY
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DOI:
10.1097/00006842-199509000-00008
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发表时间:
1995-09-01
影响因子:
3.3
通讯作者:
STONE, AA
STONE, AA
中科院分区:
医学3区
文献类型:
--
作者:
OCKENFELS, MC;PORTER, L;STONE, AA

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本研究探讨了与失业相关的慢性应激对唾液皮质醇排泄量的影响,皮质醇的昼夜节律,以及皮质醇对急性自然主义应激源的反应性,使用经验抽样方法(ESM)。对就业(N = 60)和失业(N = 60)受试者进行了为期2天的研究。受试者每天通过预先编程的手表发出6次蜂鸣声,以评估急性压力源;每次ESM蜂鸣后25分钟,受试者第二次发出蜂鸣声以获取唾液样本。两组在皮质醇总排泄量或皮质醇对急性日常压力的反应性方面没有差异。与有工作的受试者相比,失业受试者的皮质醇排泄的昼夜模式相对较高的早晨和较低的晚上水平。受试者的日常活动和他们的位置与昼夜节律差异有关。
This study examined the effect of chronic stress associated with unemployment on the magnitude of salivary cortisol excretion, on the diurnal rhythm of cortisol, and on cortisol reactivity to acute naturalistic stressors using Experience Sampling Methodology (ESM). Employed (N = 60) and unemployed (N = 60) subjects were studied for 2 days. Subjects were beeped 6 times per day by a preprogrammed wristwatch to assess acute stressors; 25 minutes after each ESM-beep, subjects were beeped a second time for saliva samples. The groups did not differ in their overall cortisol excretion or in cortisol reactivity to acute daily stressors. Compared to employed subjects, unemployed subjects had a diurnal pattern of cortisol excretion with relatively higher morning and lower evening levels. Subjects' daily activities and their locations were associated with diurnal rhythm differences.