Prevalence, severity, and health correlates of lower urinary tract symptoms among older men: The MrOS study
Prevalence, severity, and health correlates of lower urinary tract symptoms among older men: The MrOS study
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DOI：
10.1016/j.urology.2006.04.019
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发表时间：
2006-10-01
期刊：
影响因子：
2.1
通讯作者：
Orwoll, Eric S.
中科院分区：
文献类型：
--
作者：
Taylor, Brent C.;Wilt, Timothy J.;Orwoll, Eric S.
目标.描述美国社区老年男性下尿路症状（LUTS）的患病率、严重程度和健康相关性。我们对从美国六个临床中心招募的队列研究进行了横断面分析。这项分析包括5284名没有前列腺癌病史的男性，年龄至少为65岁。参与者完成了关于LUTS的存在和严重程度的问卷调查，包括美国泌尿学会症状和困扰指数。健康状况测量包括医疗结果调查SF-I 2和自测健康和工具性日常生活活动。2.3%的患者不存在LUTS，51.6%为轻度，39.6%为中度，6.6%为重度。对泌尿系统症状的不满意度随着LUTS严重程度的增加而增加（P < 0.001）; 19.8%的中度和58.1%的重度LUTS男性报告对他们目前的泌尿系统症状感到不满意到可怕。LUTS的患病率、严重程度和不满程度随着年龄的增长而增加。报告中度或重度LUTS的男性，即使在控制了年龄和共病条件后，其总体健康质量在其年龄范围内被评为一般至非常差而不是良好至极好的可能性分别为1.41倍（95%置信区间1.23至1.61）和1.51倍（95%置信区间1.23至1.85）。LUTS增加也与工具性日常生活活动障碍增加和SF-I 2评分降低独立相关。中度至重度LUTS在社区居住的美国老年男性中很常见。在这项研究中，下尿路症状的严重程度与较差的健康质量和更大的患病率，无法进行日常生活活动。LUTS严重程度与健康状况不佳的相关性值得临床关注。(c)2006年爱思唯尔公司
Objectives. To describe the prevalence, severity, and health correlates of lower urinary tract symptoms (LUTS) in older community-dwelling U.S. men.Methods. We performed a cross-sectional analysis from a cohort study recruited from six U.S. clinical centers. This analysis included 5284 men without a history of prostate cancer who were at least 65 years of age. Participants completed questionnaires regarding the presence and severity of LUTS, including the American Urological Association Symptom and Bother indexes. Health status measures included the Medical Outcomes Survey SF-I 2 and self-rated health and instrumental activities of daily living.Results. LUTS were absent in 2.3%, mild in 51.6%, moderate in 39.6%, and severe in 6.6%. Dissatisfaction with the urinary symptoms increased with LUTS severity (P < 0.001); 19.8% of moderate and 58.1% of men with severe LUTS reported feeling mostly unsatisfied to terrible with their present urinary symptoms. The prevalence, severity, and dissatisfaction with LUTS increased with age. Men reporting moderate or severe LUTS were 1.41-fold (95% confidence interval 1.23 to 1.61) and 1.51-fold (95% confidence interval 1.23 to 1.85) more likely to rate their overall health quality as fair to very poor for their age instead of good to excellent, even after controlling for age and comorbid conditions. Increased LUTS also was independently associated with increased impairment in instrumental activities of daily living and poorer SF-I 2 scores.Conclusions. Moderate-to-severe LUTS is common in community-dwelling elderly U.S. men. In this study, LUTS severity was associated with poorer health quality and a greater prevalence of an inability to perform activities of daily living. The association of LUTS severity with poor health warrants increased clinical attention. (c) 2006 Elsevier Inc.