Preparation of novel optical fibre-based Cocaine sensors using a molecular imprinted polymer approach
Preparation of novel optical fibre-based Cocaine sensors using a molecular imprinted polymer approach
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DOI：
10.1016/j.snb.2013.11.071
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发表时间：
2014-03
影响因子：
8.4
通讯作者：
S. Wren;T. H. Nguyen;P. Gascoine;R. Lacey;T. Sun;K. Grattan
中科院分区：
文献类型：
--
作者：
S. Wren;T. H. Nguyen;P. Gascoine;R. Lacey;T. Sun;K. Grattan
利用含有荧光素基团的分子印迹聚合物(MIP)作为信号基团，开发了基于光纤技术的新型化学传感器来检测可卡因。荧光分子印迹聚合物被形成，并共价连接到特别选择的光纤的远端，以创建基于光纤探头的传感器。所展示的这些传感器是可以生产的，并且可以量化地改变从传感器接收到的荧光信号的强度，以响应于乙腈混合水溶液中的可卡因。在这项工作中开发的传感器之一已经证明了可卡因对可卡因和一系列已知可卡因干扰物的高选择性。
Novel chemical sensors using fibre optic-based techniques for the detection of Cocaine have been developed, utilising molecularly imprinted polymers (MIPs) containing fluorescein moieties as the signalling groups. The fluorescent MIPs were formed and covalently attached to the distal end of specially chosen optical fibres to create fibre optic probe-based sensors. These sensors exhibited are producible and quantifiable change in the intensity of the fluorescence signal received from the sensor in response to Cocaine in aqueous acetonitrile mixtures. High selectivity for Cocaine over Codeine and a range of known Cocaine interferants has been demonstrated for one of the sensors developed in this work.