Brain Abscess Associated with Polymicrobial Infection after Intraoral Laceration: A Pediatric Case Report.
Brain Abscess Associated with Polymicrobial Infection after Intraoral Laceration: A Pediatric Case Report.
复制标题
口内撕裂后与多种微生物感染相关的脑脓肿：儿科病例报告。
DOI：
10.1155/2020/8304302
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发表时间：
2020
影响因子：
0.9
通讯作者：
Eguchi M
中科院分区：
文献类型：
--
作者：
Ochi F;Tauchi H;Miyata T;Moritani T;Chisaka T;Hamada J;Nagai K;Eguchi-Ishimae M;Eguchi M
脑脓肿是脑实质内的感染，可能是感染、创伤和手术等各种疾病的并发症。然而，儿童中由多种微生物引起的脑脓肿很少有报道。我们在此报告一例患有未解决的先天性紫绀性心脏病（CCHD）的 9 岁女孩，表现为右侧偏瘫，在口咽损伤后被诊断为由中间链球菌、微单胞菌和具核梭杆菌引起的脑脓肿。她接受了静脉抗菌治疗、开颅引流以及甘油和Goreisan抗水肿治疗，使右偏瘫改善至基线；经过八周的静脉抗菌治疗后，她出院了。由于非特异性表现，脑脓肿的临床诊断很困难，这突显了脑脓肿风险增加的患者（例如患有 CCHD 的患者）不急于进行颅脑成像的重要性，这些患者在没有局部症状的情况下出现发烧或发烧，并伴有异常的神经系统检查结果。
Brain abscesses, infections within the brain parenchyma, can arise as complications of various conditions including infections, trauma, and surgery. However, brain abscesses due to polymicrobial organisms have rarely been reported in children. We herein report a case of a 9‐year‐old girl with unresolved congenital cyanotic heart disease (CCHD) presenting with right hemiplegia who was diagnosed with brain abscess caused byStreptococcus intermedius,Parvimonas micra, andFusobacterium nucleatumafter oropharyngeal injury. She was treated with intravenous antimicrobial therapy, drainage under craniotomy, and antiedema therapy with glycerol and goreisan, which led to the improvement of right hemiplegia to baseline; she was discharged following eight weeks of intravenous antimicrobial therapy. The clinical diagnosis of the brain abscess was difficult due to the nonspecific presentation, highlighting the importance of cranial imaging without haste in patients at increased risk for brain abscesses such as those with CCHD, presenting with fever in the absence of localizing symptoms or fever, accompanied with abnormal neurological findings.