Using PGSE NMR for chemical mixture analysis: Quantitative aspects
Using PGSE NMR for chemical mixture analysis: Quantitative aspects
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DOI：
10.1002/cmr.a.20093
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发表时间：
2007-09-01
影响因子：
0.6
通讯作者：
Antalek, Brian
中科院分区：
文献类型：
--
作者：
Antalek, Brian
脉冲梯度自旋回波核磁共振结合数据处理方法，如直接指数曲线分解算法，可用于拆分混合物中的单个组分。组分的扩散系数的不同会导致它们在实验中的信号衰减行为不同，并允许分辨纯组分光谱。由于实验是以回声为基础的，不同成分中原子核的弛豫行为的差异导致了非定量光谱。因此，它很少被用来直接定量地确定各组分的水平。本文探讨了在PGSE核磁共振实验中，由于弛豫引起的信号损失的影响，并描述了一种最终从混合物中获得定量纯组份光谱的外推方法。给出了表面修饰纳米颗粒的例子。(C)2007年威利期刊公司。
Pulsed gradient spin echo NMR coupled with a data processing approach such as direct exponential curve resolution algorithm may be used to resolve individual components in a mixture. Differences in the diffusivities of the components lead to differences in their signal decay behavior in the experiment and allow for pure component spectra to be resolved. Because the experiment is echo-based, differences in the relaxation behavior of the nuclei within the various components lead to nonquantitative spectra. As a consequence it is rarely used to directly determine the levels of the components quantitatively. This article explores the effects of signal loss in the PGSE NMR experiment because of relaxation and describes an extrapolation method to ultimately obtain quantitative pure component spectra from mixtures. Examples of surface-modified nanoparticles are presented. (c) 2007 Wiley Periodicals, Inc.