Eye movements during visual search in patients with glaucoma.
Eye movements during visual search in patients with glaucoma.
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青光眼患者视觉搜索过程中的眼球运动。
DOI：
10.1186/1471-2415-12-45
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发表时间：
2012-08-31
影响因子：
2
通讯作者：
Crabb DP
中科院分区：
文献类型：
--
作者：
Smith ND;Glen FC;Crabb DP
青光眼已被证明会导致许多日常任务（包括视觉搜索）的残疾。本研究旨在确定青光眼患者的眼跳运动是否与视力正常的人不同，并调查眼球运动与视觉搜索受损之间的关联。 40 名双眼患有一系列青光眼视野 (VF) 缺陷（平均最佳眼平均偏差 [MD]：–5.9 (SD: 5.4) dB）的患者（平均年龄：67 [SD：9] 岁）和 40 名视力正常的年龄相关者（平均年龄：66 [SD：10] 岁）在计算机显示的现实世界场景照片中搜索一系列目标物体时进行了计时。使用眼动仪同时记录眼球运动。记录试验中每秒的平均眼跳次数、平均眼跳幅度和平均搜索持续时间。将这些响应变量与 VF 和对比敏感度的测量结果进行比较。在视觉搜索任务中，患者组的平均眼跳次数明显小于对照组（P = 0.02；平均减少了5.6%（95% CI：0.1至10.4%）。患者和对照组之间的平均眼跳幅度没有差异（P = 0.09）。平均眼跳次数与视觉方面的相关性较弱。对比敏感度较差（PR logCS；Spearman’s rho：0.42；P = 0.006）和更严重 VF 缺陷（最佳眼部 MD；Spearman’s rho：0.34；P = 0.037）的患者在任务期间往往会进行较少的眼球运动。搜索任务中的平均检测时间与患者组的平均眼跳率相关。 （Spearman’s rho = −0.65；P < 0.001），但这在对照组中并不明显。这组患者在视觉搜索过程中的平均眼跳率低于平均年龄相同的视力正常的人。患者的眼跳率存在很大差异，但该指标的增加与搜索任务的更好表现之间存在关联。青光眼可能有助于了解该疾病的功能缺陷。
Glaucoma has been shown to lead to disability in many daily tasks including visual search. This study aims to determine whether the saccadic eye movements of people with glaucoma differ from those of people with normal vision, and to investigate the association between eye movements and impaired visual search. Forty patients (mean age: 67 [SD: 9] years) with a range of glaucomatous visual field (VF) defects in both eyes (mean best eye mean deviation [MD]: –5.9 (SD: 5.4) dB) and 40 age-related people with normal vision (mean age: 66 [SD: 10] years) were timed as they searched for a series of target objects in computer displayed photographs of real world scenes. Eye movements were simultaneously recorded using an eye tracker. Average number of saccades per second, average saccade amplitude and average search duration across trials were recorded. These response variables were compared with measurements of VF and contrast sensitivity. The average rate of saccades made by the patient group was significantly smaller than the number made by controls during the visual search task (P = 0.02; mean reduction of 5.6% (95% CI: 0.1 to 10.4%). There was no difference in average saccade amplitude between the patients and the controls (P = 0.09). Average number of saccades was weakly correlated with aspects of visual function, with patients with worse contrast sensitivity (PR logCS; Spearman’s rho: 0.42; P = 0.006) and more severe VF defects (best eye MD; Spearman’s rho: 0.34; P = 0.037) tending to make less eye movements during the task. Average detection time in the search task was associated with the average rate of saccades in the patient group (Spearman’s rho = −0.65; P < 0.001) but this was not apparent in the controls. The average rate of saccades made during visual search by this group of patients was fewer than those made by people with normal vision of a similar average age. There was wide variability in saccade rate in the patients but there was an association between an increase in this measure and better performance in the search task. Assessment of eye movements in individuals with glaucoma might provide insight into the functional deficits of the disease.
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DOI：
10.1007/s00417-004-0984-x
发表时间：
2005-03-01
影响因子：
2.7
作者：
Crabb, DP;Viswanathan, AC
通讯作者：
Viswanathan, AC
影响因子：
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Geisler, Wilson S.;Perry, Jeffrey S.;Najemnik, Jiri
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Najemnik, Jiri
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Barth, Erhardt
影响因子：
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作者：
Hawkins, AS;Szlyk, JP;Wilensky, JT
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Wilensky, JT