Association Between Estimated Glomerular Filtration Rate Based on Cystatin C and Grip Strength in Community-Dwelling Japanese Older Adults
Association Between Estimated Glomerular Filtration Rate Based on Cystatin C and Grip Strength in Community-Dwelling Japanese Older Adults
复制标题
DOI：
10.1093/gerona/glaa240
复制
发表时间：
2021-09-01
影响因子：
5.1
通讯作者：
Narita, Ichiei
中科院分区：
文献类型：
--
作者：
Kabasawa, Keiko;Nakamura, Kazutoshi;Narita, Ichiei
Background: Kidney dysfunction is associated with sarcopenia. Estimated glomerular filtration rate based on cystatin C (eGFR(cys)), an alternative to creatinine-based measures of kidney function eGFR, is not affected by muscle mass. Given that the association of eGFR(cys) with muscle weakness would be limited, we examined the association in older adults with normal or compromised kidney function.Methods: This cross-sectional study involved 594 community-dwelling Japanese adults aged >= 40 years living in Yuzawa, Japan. Serum creatinine, cystatin C, and handgrip strength were concurrently measured at a health-check examination in 2015. eGFR was calculated according to the equation developed for the Japanese population using creatinine and cystatin C. Associations of eGFR(cys) and eGFR(creat) with low grip strength (men,
