Toxicity of pesticides in wastewater:: a comparative assessment of rapid bioassays
Toxicity of pesticides in wastewater:: a comparative assessment of rapid bioassays
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DOI：
10.1016/s0003-2670(00)00874-6
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发表时间：
2001-01-12
影响因子：
6.2
通讯作者：
Chisti, Y
中科院分区：
文献类型：
--
作者：
Fern치ndez-Alba, AR;Guil, LH;Chisti, Y
使用发光细菌费氏弧菌、水生无脊椎动物大型蚤的各种反应和MitoScan（TM）测定法，单独和混合评估了水中农药的急性毒性。后者利用片段化的线粒体将氧化的β-烟酰胺腺嘌呤二核苷酸（NAD（+））酶促转化为其还原形式NADH。转化率对毒物的种类和浓度敏感。测试的农药是克百威、灭蝇胺、灭线磷、甲氰菊酯和霜霉威。所有化合物的水溶解度均超过320 mg l（-1）。所有毒性生物测定均以相对灵敏度和互补性为特征。与纯化合物毒性相比，农药混合物观察到协同和拮抗毒性效应。地方magna试验是最敏感的，最能检测混合物的毒性相互作用。灭蝇胺是测试的农药中毒性最小的。(C)2001 Elsevier Science B. V.保留所有权利。
Acute toxicity of pesticides in water was assessed singly and in mixtures using various responses of the luminescent bacterium Vibrio fischeri, the aquatic invertebrate Daphnia magna, and the MitoScan(TM) assay. The latter utilized fragmented mitochondria to enzymatically convert oxidized beta -nicotinamide adenine dinucleotide (NAD(+)) to its reduced form, NADH. The rate of the conversion being sensitive to the type and concentration of toxicants. The pesticides tested were carbofuran, cyromazine, fenamiphos, formetanate, and propamocarb. The aqueous solubility of all compounds exceeded 320 mg l(-1). All the toxicity bioassays were characterized in terms of relative sensitivity and complementarity. Synergistic and antagonistic toxicity effects were observed with pesticide cocktails relative to pure compound toxicities. The D. magna assay was the most sensitive and best able to detect toxic interactions of mixtures. Cyromazine was the least toxic of the pesticides tested. (C) 2001 Elsevier Science B.V. All rights reserved.