Neurobiology of Grooming Behavior: An ethological analysis of barbering behavior
Neurobiology of Grooming Behavior: An ethological analysis of barbering behavior
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理发行为的神经生物学：理发行为的行为学分析
DOI：
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发表时间：
2010
期刊：
影响因子：
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通讯作者：
J. Garner
中科院分区：
文献类型：
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作者：
Brett D. Dufour;J. Garner
总结“理发”是小鼠的一种异常行为。发鼠从笼友和/或自己身上拔毛和/或胡须，留下特殊的脱毛斑块。这种行为是自相矛盾的：在实验室小鼠中，毛发修剪是常见的，但在野生小鼠中没有发现，它对拔毛者没有好处，并且对接受者来说是昂贵的。本章将试图通过询问理发行为是如何发生的以及为什么会发生来解决理发悖论。使用Tinbergen（1963）的行为学分析框架，我们评估理发的适应功能，生殖，发展和机制。第一节讨论适应函数的假设。优势假说被几项研究反驳;应对假说尚未得到检验;病理学假说得到多方面证据的支持。因此，病理学假说为理发悖论提供了最好的解决方案。因此，在整个过程中，我们比较和对比理发，脱毛症（TTM）和其他人类疾病的特点是重复的行为。第二部分通过比较和对比不同物种和小鼠品系之间的拔毛行为来评估理发的系统发育基础。第三部分回顾了理发行为的发展过程，特别是发展的风险因素，学习，实验室环境和转基因的影响。最后一节回顾了行为机制，引发刺激，和生理机制，可能介导理发。在这里，我们概述了皮质-纹状体回路在异常重复行为中的作用，它如何被用来描述疾病，以及它为理发提供的见解。
Summary “Barbering” is an abnormal behavior in mice. Barbering mice pluck fur and/or whiskers from cage-mates and/or themselves, leaving idiosyncratic patches of hair loss. The behavior is a paradox: barbering is common in laboratory mice, but it is not seen in wild mice, it does not benefit the plucker, and it is costly to the recipient. This chapter will attempt to resolve the barbering paradox by asking how and why barbering behavior occurs. Using Tinbergen's (1963) framework for an ethological analysis, we assess barbering in terms of adaptive function, phylogeny, development, and mechanism. The first section discusses hypotheses of adaptive function. The dominance hypothesis is refuted by several studies; the coping hypothesis remains untested; and the pathology hypothesis is supported by multiple lines of evidence. The pathology hypothesis therefore provides the best resolution to the barbering paradox. Accordingly, throughout, we compare and contrast barbering to trichotillomania (TTM) and other human disorders characterized by repetitive behavior. The second section assesses the phylogenetic underpinnings of barbering by comparing and contrasting hair-plucking behavior across species and between mouse strains. The third section reviews the developmental processes that underlie barbering behavior, particularly developmental risk factors, learning, the laboratory environment, and transgenic effects. The final section reviews the behavioral mechanisms, eliciting stimuli, and physiological mechanisms that might mediate barbering. Here, we outline the role of cortico–striatal circuitry in abnormal repetitive behavior in general, how it can be used to delineate disorders, and insights it provides into barbering.
影响因子：
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作者：
Peterson, BS;Thomas, P;Staib, L
通讯作者：
Staib, L