Biological and nonbiological modifications of organophosphorus compounds.
Biological and nonbiological modifications of organophosphorus compounds.
复制标题
有机磷化合物的生物和非生物修饰。
DOI：
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发表时间：
1971
影响因子：
11.1
通讯作者：
W. Dauterman
中科院分区：
文献类型：
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作者：
W. Dauterman
在有机磷化合物的改性中最突出的生物反应的一般类型涉及混合功能氧化酶、水解酶或转移酶。在某些情况下，在农药分子上的同一位点可能涉及一种以上的这些反应。各种有机磷农药的氧化，水解，烷基或芳基基团转移，还原和共轭改变的例子进行了讨论。着重介绍了生物改性可引起农药毒性的增加或降低，有机磷化合物的非生物转化涉及光、空气、温度和溶剂等因素对化合物的影响。这些因素进行了讨论，特别强调脱硫，重排和氧化。
The general types of biological reaction that are most prominent in the modification of organophosphorus compounds involve the mixed-function oxidases, hydrolases, or transferases. In certain cases, more than one of these reactions may be involved at the same site on the pesticide molecule. Examples of various organophosphorus pesticides that are altered by oxidation, hydrolysis, alkyl- or aryl-group transfer, reduction, and conjugation are discussed. The increase or decrease in toxicity of a pesticide that can result from biological modification is emphasized.Non-biological transformations of organophosphorus compounds involve the effect ou the compounds of such factors as light, air, temperature, and solvent. These factors are discussed with special emphasis on desulfuration, rearrangement, and oxidation.