PREDICTING CORONARY HEART-DISEASE IN MIDDLE-AGED AND OLDER PERSONS - FRAMINGTON STUDY
PREDICTING CORONARY HEART-DISEASE IN MIDDLE-AGED AND OLDER PERSONS - FRAMINGTON STUDY
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DOI：
10.1001/jama.238.6.497
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发表时间：
1977-01-01
影响因子：
120.7
通讯作者：
DAWBER, TR
中科院分区：
文献类型：
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作者：
GORDON, T;CASTELLI, WP;DAWBER, TR
在年龄49-82岁的1025名男性和1445名女性中，79名男性和63名女性随后患上了冠心病。使用基于高密度和低密度脂蛋白、收缩压、左心室肥厚和糖尿病的胆固醇的风险函数，不到2%的后续CHD病例被发现处于风险最低的分位数，而25%的男性和37%的女性病例被发现在风险分位数的最高分位数。每个特定年龄段的可预测性。这种可预测性至少与年轻时通常的CHD风险状况一样好。
Of 1025 men and 1445 women, aged 49-82 yr, who were free of coronary heart disease (CHD), 79 men and 63 women subsequently had CHD. Using a risk function based on cholesterol in the high density and low density lipoproteins, systolic blood pressure, left ventricular hypertrophy, and diabetes, less than 2% of the subsequent CHD cases were found in the lowest decile of risk, whereas 25% of the cases for men and 37% for women were found in the highest decile. Predictability held for each specific age group. This predictability was at least as good as that obtained by the usual CHD risk profile at younger ages.