Detection and identification of cancers by the electronic nose.
Detection and identification of cancers by the electronic nose.
复制标题
DOI：
10.1517/17530059.2012.665870
复制
发表时间：
2012-05-01
期刊：
影响因子：
--
通讯作者：
Sterk, Peter Jason
中科院分区：
文献类型：
--
作者：
D'Amico, Arnaldo;Di Natale, Corrado;Sterk, Peter Jason
前言：严重疾病的早期诊断一直是医学和社会领域的一个重要问题。对能够检测癌症的仪器的搜索导致了对人体化学物质的使用的考虑，这种化学物质通过其挥发性化合物携带来自或与特定病原体相关的信息。内容涵盖：电子鼻(EN)似乎是检测不同类型癌症的良好解决方案。最近的结果表明，EN可以用来闻到与肺癌、黑色素瘤、前列腺癌、乳腺癌和胰腺癌有关的化学物质。从ENS获得的结果是化学图像，正如本文将显示的那样，识别癌症的可能性相当高。本文将对国际上和本文作者所取得的主要成果进行评论。专家意见：对嗅觉策略的未来发展提出个人意见。为此，主要考虑了两个方面：寻找更好的EN的整体稳定性和在检测血液和病理成分之间的变化方面的新用途。
INTRODUCTION: The early determination of serious pathologies has so far been an important issue in both the medical and social fields. The search for an instrument able to detect cancers has led to the consideration of the usage of chemicals of the human body, which carry, through its volatile compounds, information coming from or related to defined pathologies.AREAS COVERED: The electronic nose (EN) seems to represent a good solution for the detection of cancers of different types. Recent results showed the utility of an EN to smell chemicals related to lung, melanoma, prostatic, breast and pancreatic cancers. The results obtainable from ENs are chemical images and, as it will be shown in this paper, the probability of cancer recognition is rather high. Main results obtained at international level and by the authors of this paper will be commented upon.EXPERT OPINION: A personal opinion is given trying to foresee future developments of the olfaction strategy. To this purpose, two main aspects are considered: looking for better overall stability of the EN and for a new use of ENs in detecting alterations between blood and pathology components.