Ancient DNA suggests the leading role played by men in the Neolithic dissemination
Ancient DNA suggests the leading role played by men in the Neolithic dissemination
复制标题
DOI：
10.1073/pnas.1113061108
复制
发表时间：
2011-11-08
影响因子：
11.1
通讯作者：
Ludes, Bertrand
中科院分区：
文献类型：
--
作者：
Lacan, Marie;Keyser, Christine;Ludes, Bertrand
新石器时代的迁徙对西欧人口的影响一直是争论的焦点。为了追踪和确定在这一转变过程中可能带来的遗传谱系，从而了解当前人群基因库的起源，我们研究了从公元前五千年初在西班牙葬礼洞穴中挖掘的人类遗骸中提取的DNA。我们获得了关于新石器时代早期丧葬习俗和被埋葬个体的生物地理起源的信息。没有发现近亲关系。发现的母系单倍群与新石器时代前的定居一致，而y染色体分析证实了大约7000年前在西班牙存在两个与新石器时代过渡有关的单倍群：G2a和E1b1b1a1b。这些结果与之前在法国新石器时代晚期新石器时代个体中发现的结果高度一致，表明这些群体中存在令人惊讶的时间遗传同质性。此外，在西欧的新石器时代样本中，G2a的高频率可能表明，在新石器时代的传播过程中，男性的作用可能比目前估计的要大。
The impact of the Neolithic dispersal on the western European populations is subject to continuing debate. To trace and date genetic lineages potentially brought during this transition and so understand the origin of the gene pool of current populations, we studied DNA extracted from human remains excavated in a Spanish funeral cave dating from the beginning of the fifth millennium B.C. Thanks to a "multimarkers" approach based on the analysis of mitochondrial and nuclear DNA (autosomes and Y-chromosome), we obtained information on the early Neolithic funeral practices and on the biogeographical origin of the inhumed individuals. No close kinship was detected. Maternal haplogroups found are consistent with pre-Neolithic settlement, whereas the Y-chromosomal analyses permitted confirmation of the existence in Spain approximately 7,000 y ago of two haplogroups previously associated with the Neolithic transition: G2a and E1b1b1a1b. These results are highly consistent with those previously found in Neolithic individuals from French Late Neolithic individuals, indicating a surprising temporal genetic homogeneity in these groups. The high frequency of G2a in Neolithic samples in western Europe could suggest, furthermore, that the role of men during Neolithic dispersal could be greater than currently estimated.