Safety and efficacy of total dose infusion of 1,020 mg of ferumoxytol administered over 15 min
Safety and efficacy of total dose infusion of 1,020 mg of ferumoxytol administered over 15 min
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DOI：
10.1002/ajh.23534
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发表时间：
2013-11-01
影响因子：
12.8
通讯作者：
Bahrain, Huzefa
中科院分区：
文献类型：
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作者：
Auerbach, Michael;Strauss, William;Bahrain, Huzefa
对于大多数缺铁性贫血（IDA）患者，静脉（IV）铁的整个疗程为1g。大多数静脉注射铁需要5-10次100-300毫克。我们已经成功地在1小时内使用了1g低分子量的右旋糖酐铁。为了进一步方便患者和医生，我们探索了1.02 g阿魏木醇超过15分钟的给药，而不是批准的2 x 510 mg注射。60例IDA患者，血红蛋白
For the majority of patients with iron deficiency anemia (IDA), a full course of intravenous (IV) iron is 1 g. Most IV irons require 5-10 administrations of 100-300 mg. We have successfully employed 1 g low molecular weight iron dextran over 1 hr. For further convenience for patients and physicians, we explored the administration of 1.02 g of ferumoxytol over 15 min instead of the approved 2 x 510 mg injections. Sixty patients with IDA, (hemoglobin