Ruthenium-catalyzed conversion of levulinic acid to pyrrolidines by reductive amination.
Ruthenium-catalyzed conversion of levulinic acid to pyrrolidines by reductive amination.
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DOI：
10.1002/cssc.201100344
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发表时间：
2011-11
期刊：
影响因子：
8.4
通讯作者：
Yao-Bing Huang;Jian-Jun Dai;Xiao‐Jian Deng;Y. Qu;Q. Guo;Yao Fu
中科院分区：
文献类型：
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作者：
Yao-Bing Huang;Jian-Jun Dai;Xiao‐Jian Deng;Y. Qu;Q. Guo;Yao Fu
当前全球对不可再生化石燃料的大规模消费正迫使学术界和工业界科学家寻找替代的可持续资源。将生物质转化为燃料和增值化学品可能对这一努力至关重要，近年来一直是一个强有力的研究重点。碳水化合物是生物质的主要成分，可以转化为乙醇、羟甲基呋喃(HMF)、乙酰丙酸(LA)和呋喃等多种化学物质。乙酰丙酸是一种重要的平台化学品，也可由糠醇或生物质原料大规模水解生产。此外，通过氧化、还原、缩合和酯化反应，LA很有希望成为许多不同的有用中间体和精细化学品的起始原料(方案1)。例如，g-戊内酯可用作液体燃料、食品添加剂和溶剂；5-氨基乙酰丙酸是一种活性高、可生物降解、无毒的除草剂和杀虫剂。
The current global mass consumption of non-renewable fossil fuels is forcing academic and industrial scientists to find alternative sustainable resources. The transformation of biomass into fuels and value-added chemicals could be crucial to this endeavour and has been a strong research focus in recent years. Carbohydrates, the main component of biomass, could be converted into many chemicals such as ethanol, hydroxymethylfurfural (HMF), levulinic acid (LA), and furfural. Levulinic acid, an important platform chemical, can also be produced by large-scale hydrolysis of furfurylalcohol or biobased cellulosic feedstocks. Moreover, LA is a promising starting material for many different useful intermediates and fine chemicals by oxidation, reduction, condensation, and esterification (Scheme 1). For example, g-valerolactone may be used as a liquid fuel, food additive and solvent; 5-aminolevulinic acid is a highly active, biodegradable, and nontoxic herbicide and insecticide.