Electrochemical separation of organic acids and proteins for food and biomanufacturing
Electrochemical separation of organic acids and proteins for food and biomanufacturing
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DOI：
10.1016/j.cherd.2021.12.009
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发表时间：
2022-02-01
影响因子：
3.9
通讯作者：
Su, Xiao
中科院分区：
文献类型：
--
作者：
Kim, Nayeong;Jeon, Jemin;Su, Xiao
在过去的几十年里，人口的快速增长加上对营养的认识的提高推动了对有机酸（例如，羧酸盐）和蛋白质，通过药物和食品。有机酸和蛋白质总生产成本的近50-70%来自生产过程中的分离过程。最近，电化学介导的分离作为降低化学品消耗和实现过程强化的可持续解决方案获得了极大的关注。在这里，我们回顾了在食品和生物制造背景下，用于回收有机酸和蛋白质的电化学过程的进展。我们强调这些系统的电化学工程方面，电极材料的选择，并讨论了潜在的分离机制。我们强调需要了解分子水平的选择性与工程设计相结合，扩大电化学平台的选择性生物产品纯化的适用性。从长远来看，我们认为电化学分离是回收食品和生物制造中增值分子的可持续和有竞争力的过程。(c)2021化学工程师学会。Elsevier B. V.出版，保留所有权利。
Over the past decades, the rapid population growth coupled with increased awareness towards nutrition has driven the demand for organic acids (e.g., carboxylates) and proteins, through pharmaceutical and food products. Close to 50-70% of the overall production cost of organic acids and proteins comes from separation processes during manufacturing. Recently, electrochemically-mediated separations have gained significant attention as a sustainable solution for lowering chemical consumption and achieving process intensification. Here, we review progress in electrochemical processes for the recovery of organic acids and proteins, in food and biomanufacturing contexts. We highlight aspects of the electrochemical engineering of these systems, selection of electrode materials, and discuss the underlying separation mechanisms. We emphasize the need for understanding molecular level selectivity coupled with engineering design, for broadening the applicability of electrochemical platforms for selective bioproduct purification. On the long term, we envision electrochemical separations as a sustainable and competitive process for the recovery of value-added molecules in food and biomanufacturing.(c) 2021 Institution of Chemical Engineers. Published by Elsevier B.V. All rights reserved.