Campylobacter pyloridis in peptic ulcer disease. I. Gastric and duodenal infection caused by C. pyloridis: histopathologic and microbiologic findings.
Campylobacter pyloridis in peptic ulcer disease. I. Gastric and duodenal infection caused by C. pyloridis: histopathologic and microbiologic findings.
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消化性溃疡病中的幽门弯曲杆菌。
DOI：
10.3109/00365528708991883
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发表时间：
1987
影响因子：
1.9
通讯作者：
T. Justesen
中科院分区：
文献类型：
--
作者：
L. Andersen;S. Holck;C. Povlsen;L. Elsborg;T. Justesen
本文对153例消化不良患者进行了胃窦和十二指肠活检。对所有标本进行组织病理学和微生物学研究，以确定是否存在幽门弯曲菌，并根据Morson标准记录炎症类型。C.在靠近上皮细胞的粘液下发现幽门炎，并且大多数与粒细胞浸润（活动性胃炎）有关。C. 10例活动性胃炎和活动性胃炎患者的幽门螺杆菌培养阳性率均为10%，64例十二指肠形态正常的活动性胃炎患者的幽门螺杆菌培养阳性率为86%，79例十二指肠形态无改变的患者的幽门螺杆菌培养阳性率仅为5%。活动性胃炎与C. pylororrhea表明C.幽门螺杆菌在胃炎症中起重要作用，因为它符合局部细菌感染的标准。
In this study 153 patients with dyspepsia were biopsied in the gastric antrum and duodenum. All specimens were investigated histopathologically and microbiologically for the presence of Campylobacter pyloridis, and the type of inflammation was recorded in accordance with Morson's criteria. C. pyloridis was found beneath the mucus close to the epithelial cells and mostly in connection with granulocytic infiltration (active gastritis). C. pyloridis was cultured from all of 10 patients with histologically active gastritis and active duodenitis, in 86% of 64 patients with active gastritis and morphologically normal duodenum, and in only 5% of 79 patients without morphologic gastric and duodenal changes. The close relation between active gastritis and C. pyloridis shows that C. pyloridis plays an important role in gastric inflammation, as it fulfils the criterion for a localized bacterial infection.