Health-related quality of life and disease-specific complaints among multiple myeloma patients up to 10 yr after diagnosis: results from a population-based study using the PROFILES registry
Health-related quality of life and disease-specific complaints among multiple myeloma patients up to 10 yr after diagnosis: results from a population-based study using the PROFILES registry
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DOI：
10.1111/j.1600-0609.2012.01831.x
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发表时间：
2012-10-01
影响因子：
3.1
通讯作者：
van de Poll-Franse, Lonneke V.
中科院分区：
文献类型：
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作者：
Mols, Floortje;Oerlemans, Simone;van de Poll-Franse, Lonneke V.
背景 这项基于人群的前瞻性研究描述了多发性骨髓瘤 (MM) 患者诊断后 10 年内的健康相关生活质量 (HRQOL) 和疾病特异性主诉。方法 使用埃因霍温癌症登记处选择 1999 年至 2010 年诊断为 MM 的所有患者。 MM 患者在基线时（n=156；74% 应答率）和一年后（n=80）完成了 EORTC QLQ-C30 和 EORTC QLQ-MY20 问卷调查。 EORTC QLQ-C30 也是由年龄和性别匹配的正常人群 (n=500) 完成的。结果 MM 患者在所有 EORTC QLQ-C30 量表上报告了统计显着且临床相关的较差分数（所有 P 至少
Background This prospective population-based study describes health-related quality of life (HRQOL) and disease-specific complaints of patients with multiple myeloma (MM) up to 10 similar to yr post-diagnosis. Methods The Eindhoven Cancer Registry was used to select all patients diagnosed with MM from 1999 to 2010. Patients with MM completed the EORTC QLQ-C30 and EORTC QLQ-MY20 questionnaires at baseline (n=156; 74% response rate) and 1yr later (n=80). The EORTC QLQ-C30 was also completed by an age- and sex-matched normative population (n=500). Results Patients with MM reported statistically significant and clinically relevant worse scores on all EORTC QLQ-C30 scales (all P's at least