On the characterization of sodium alginate/gelatine-based hydrogels for wound dressing
On the characterization of sodium alginate/gelatine-based hydrogels for wound dressing
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DOI：
10.1002/app.36590
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发表时间：
2012-10-25
影响因子：
3
通讯作者：
Saha, Petr
中科院分区：
文献类型：
--
作者：
Saarai, Amarjargal;Sedlacek, Tomas;Saha, Petr
在这项研究中，海藻酸钠/明胶（SA/G）水凝胶制备的伤口敷料具有良好的，潮湿的，愈合，和生物相容性。通过扫描电子显微镜、傅立叶变换红外光谱和溶胀试验对水凝胶的物理化学性质进行了评价。动态粘弹性能，包括储能模量、损耗模量、G'和G？，在振荡实验中检测了新鲜制备的和溶胀的凝胶的损耗角、tan δ。其结果表明，测试的SA/G水凝胶表现出类似于人类皮肤的粘弹性响应的高弹性行为。根据所进行的分析，可以认为SA/G水凝胶是一种潜在的伤口敷料材料，可提供并维持防止结痂形成和伤口床脱水所需的足够潮湿环境。(c)2012 Wiley Periodicals，Inc.应用聚合物科学杂志，2012年
In this study, sodium alginate/gelatine (SA/G) hydrogels were prepared to obtain wound dressing with good, moist, healing, and biocompatibility properties. The physicochemical properties of hydrogels were evaluated by scanning electron microscopy, Fourier transform infrared spectroscopy, and a swelling test. Dynamic viscoelastic properties including the storage, loss moduli, G' and G?, and loss angle, tan delta of both freshly prepared and swelled gels were examined in oscillatory experiments. Its results revealed that tested SA/G hydrogels exhibit highly elastic behavior similar to the viscoelastic response of human skin. Based on the performed analysis, it could be suggested that the SA/G hydrogel is a potential wound dressing material providing and maintaining the adequate moist environment required to prevent scab formation and the dehydration of the wound bed. (c) 2012 Wiley Periodicals, Inc. J Appl Polym Sci, 2012