Integrase Inhibitor Prescribing Disparities in the DC and Johns Hopkins HIV Cohorts.
Integrase Inhibitor Prescribing Disparities in the DC and Johns Hopkins HIV Cohorts.
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DOI：
10.1093/ofid/ofab338
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发表时间：
2021-08
影响因子：
4.2
通讯作者：
DC Cohort Executive Committee
中科院分区：
文献类型：
--
作者：
Monroe AK;Levy ME;Greenberg AE;Keruly JC;Moore RD;Horberg MA;Kulie P;Mohanraj BS;Kumar PN;Castel AD;DC Cohort Executive Committee
整合酶抑制剂（INSTIs）被专家小组推荐作为HIV感染者的初始治疗。由于在处方和接受新的和/或推荐的治疗方面可能存在差异，因此本分析使用来自约翰霍普金斯HIV临床队列和DC队列的合并数据集评估了潜在的HIV I处方差异。我们进行了多变量逻辑回归分析，以确定与曾经被处方的CIMI相关的因素。注意到差异，包括诊所位置，年龄和变性。识别差异可以使临床医生将注意力集中在这些个体上，并确保治疗决策基于有效的临床原因。我们使用约翰霍普金斯HIV临床队列/DC队列数据评估了TBI处方差异。注意到差异，包括诊所位置，年龄和变性。临床医生应该把注意力集中在这些人身上，并根据有效的临床原因做出治疗决定。
Integrase inhibitors (INSTIs) are recommended by expert panels as initial therapy for people with HIV. Because there can be disparities in prescribing and uptake of novel and/or recommended therapies, this analysis assessed potential INSTI prescribing disparities using a combined data set from the Johns Hopkins HIV Clinical Cohort and the DC Cohort. We performed multivariable logistic regression to identify factors associated with ever being prescribed an INSTI. Disparities were noted, including clinic location, age, and being transgender. Identifying disparities may allow clinicians to focus their attention on these individuals and ensure that therapy decisions are grounded in valid clinical reasons. We assessed INSTI prescribing disparities using Johns Hopkins HIV Clinical Cohort/DC Cohort data. Disparities were noted, including clinic location, age, and being transgender. Clinicians should focus their attention on these individuals and make therapy decisions grounded in valid clinical reasons.
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基于整合酶抑制剂的方案在未经治疗的人类免疫缺陷病毒感染的患者中与非核苷和蛋白酶抑制剂基于蛋白酶的临床环境相比，病毒性抑制率更快：回顾性队列研究。
影响因子：
1.6
作者：
Jacobson K;Ogbuagu O
通讯作者：
Ogbuagu O
影响因子：
3.7
作者：
Messiaen P;Wensing AM;Fun A;Nijhuis M;Brusselaers N;Vandekerckhove L
通讯作者：
Vandekerckhove L
影响因子：
6.4
作者：
Meditz, Amie L.;MaWhinney, Samantha;Connick, Elizabeth
通讯作者：
Connick, Elizabeth
影响因子：
8.5
作者：
Castel, Amanda D.;Terzian, Arpi;Greenberg, Alan
通讯作者：
Greenberg, Alan
影响因子：
3.8
作者：
Sevelius, Jae M.;Patouhas, Enzo;Keatley, JoAnne G.;Johnson, Mallory O.
通讯作者：
Johnson, Mallory O.