Ultrafast Spreading Efect Induced Rapid Cell Trapping int Porous Scaffold with Superhydrophilic Surface
Ultrafast Spreading Efect Induced Rapid Cell Trapping int Porous Scaffold with Superhydrophilic Surface
复制标题
超快扩散效应诱导快速细胞捕获于具有超亲水表面的多孔支架中
DOI：
10.1021/acsami.5b04009
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发表时间：
2015
期刊：
影响因子：
--
通讯作者：
Hongchen Sun
中科院分区：
文献类型：
--
作者：
Chenmiao Wang;Chunyan Qiao;Wenlong Song;Hongchen Sun
在这项贡献中，制造了具有超快铺展特性的超亲水性壳聚糖基支架，并用于提高细胞的捕获效率。超快的扩散特性使细胞能够更快、更有效地被捕获到所制备的支架的内部 3D 多孔结构中。细胞粘附、生长和增殖也得到改善，这可归因于紫外线照射和超快扩散特性的结合。在支架表面构建超快铺展特性将为组织工程中设计更有效的支架提供一种新方法，从而大大缩短患者的治疗时间。
In this contribution, superhydrophilic chitosan-based scaffolds with ultrafast spreading property were fabricated and used to improve the trapped efficiency of cells. The ultrafast spreading property allowed cells to be trapped into the internal 3D porous structures of the prepared scaffolds more quickly and effectively. Cell adhesion, growth, and proliferation were also improved, which could be attributed to the combination of UV irradiation and ultrafast spreading property. The construction of ultrafast spreading property on the scaffold surface will offer a novel way to design more effective scaffold in tissue engineering that could largely shorten the therapeutic time for patients.