Forehead versus forearm skin vascular responses at presyncope in humans
Forehead versus forearm skin vascular responses at presyncope in humans
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DOI：
10.1152/ajpregu.00204.2014
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发表时间：
2014-10-01
影响因子：
2.8
通讯作者：
Crandall, Craig G.
中科院分区：
文献类型：
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作者：
Gagnon, Daniel;Brothers, R. Matthew;Crandall, Craig G.
人类晕厥前常出现面部苍白，表明面部皮肤血流量 (SkBF) 减少。然而，在前臂测量时，晕厥前的皮肤血管收缩通常很小。我们测试了晕厥前额 SkBF 的减少幅度大于前臂的假设。在 11 名常温受试者和 13 名热应激受试者（肠温升高约 1.4°C）期间，在下半身负压 (LBNP) 至晕厥前的过程中，测量了前额和前臂 SkBF（激光多普勒）和血压（Finometer 或桡动脉导管插入术）。 LBNP 将正常体温期间的平均动脉压从 91 +/- 5 降低至 57 +/- 7 mmHg (P
Facial pallor is commonly observed at presyncope in humans, suggestive of reductions in facial skin blood flow (SkBF). Yet, cutaneous vasoconstriction is usually minimal at presyncope when measured at the forearm. We tested the hypothesis that reductions in forehead SkBF at presyncope are greater than in the forearm. Forehead and forearm SkBF (laser-Doppler) and blood pressure (Finometer or radial artery catheterization) were measured during lower body negative pressure (LBNP) to presyncope in 11 normothermic and 13 heat-stressed subjects (intestinal temperature increased similar to 1.4(circle)C). LBNP reduced mean arterial pressure from 91 +/- 5 to 57 +/- 7 mmHg during normothermia (P