Highly Efficient Synthesis of Unsymmetrical 3,3′‐Bis(1H‐indol‐3‐yl)methanes in Water
Highly Efficient Synthesis of Unsymmetrical 3,3′‐Bis(1H‐indol‐3‐yl)methanes in Water
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DOI：
10.1002/cjoc.201200496
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发表时间：
2012-10
影响因子：
5.4
通讯作者：
Hua-Chen Lin;Yang Zang;Xingwen Sun;G. Lin
中科院分区：
文献类型：
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作者：
Hua-Chen Lin;Yang Zang;Xingwen Sun;G. Lin
以吲哚和3-吲哚基取代苯酞为原料，在刘易斯酸InBr 3催化下，通过Friedel-Crafts反应合成了不对称双吲哚甲烷（BIM）.
A simple and practical approach for the preparation of unsymmetric bis(indolyl)methanes (BIMs) was realized by Lewis acid InBr3-catalyzed Friedel-Crafts reaction of indoles with 3-indolyl-substituted phthalides in water.