NMR CHEMICAL-SHIFT IMAGING IN 3 DIMENSIONS
NMR CHEMICAL-SHIFT IMAGING IN 3 DIMENSIONS
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DOI：
10.1073/pnas.79.11.3523
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发表时间：
1982-01-01
期刊：
影响因子：
--
通讯作者：
UGURBIL, K
中科院分区：
文献类型：
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作者：
BROWN, TR;KINCAID, BM;UGURBIL, K
本文提出了一种利用傅里叶变换核磁共振技术获得空间非均匀样品化学位移三维分布的方法。该方法使用一系列脉冲场梯度来测量（k，t）空间中矩形网格上所需分布的傅立叶变换。简单的傅立叶逆然后恢复原始分布。在20 kG [kilogauss]的场和2 cm分辨率下，10 min内获得的10 mM磷酸化代谢物分布图像的估计信噪比为20。
A method for obtaining the 3-dimensional distribution of chemical shifts in a spatially inhomogeneous sample using Fourier transform NMR is presented. The method uses a sequence of pulsed field gradients to measure the Fourier transform of the desired distribution on a rectangular grid in (k,t) space. Simple Fourier inversion then recovers the original distribution. An estimated signal/noise ratio of 20 in 10 min is obtained for an image of the distribution of a 10 mM phosphorylated metabolite in the human head at a field of 20 kG [kilogauss] with 2 cm resolution.