Validation of a computational model of cardiac defibrillation
Validation of a computational model of cardiac defibrillation
复制标题
心脏除颤计算模型的验证
DOI:
--
复制
发表时间:
2013
期刊:
影响因子:
--
通讯作者:
F. Fenton
中科院分区:
文献类型:
--
作者:
Jean Bragard;J. Elorza;E. Cherry;F. Fenton
We develop and validate a three-dimensional model of ventricular fibrillation for use in studying defibrillation. Specifically, we use a rabbit ventricular geometry as a realistic model system for evaluating the efficacy of defibrillatory shocks. Data obtained from the simulations are analyzed in terms of a dose-response curve. In agreement with clinically relevant values, we find that an electric field strength of about 6.6 V/cm indicates a 50% probability of successful defibrillation for a 12-ms monophasic shock in our model. Our validated model will be useful for optimizing defibrillation protocols and for performing detailed studies of defibrillation mechanisms.
影响因子:
3.4
作者:
Iyer, V;Mazhari, R;Winslow, RL
通讯作者:
Winslow, RL
DOI:
10.1152/ajpheart.00747.2003
发表时间:
2004-06-01
影响因子:
4.8
作者:
Cherry, EM;Fenton, FH
通讯作者:
Fenton, FH