Concurrent 2009 Pandemic Influenza A (H1N1) Virus Infection in Ferrets and in a Community in Pennsylvania
Concurrent 2009 Pandemic Influenza A (H1N1) Virus Infection in Ferrets and in a Community in Pennsylvania
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DOI：
10.1111/j.1863-2378.2012.01503.x
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发表时间：
2013-03-01
影响因子：
2.4
通讯作者：
Ostroff, S. M.
中科院分区：
文献类型：
--
作者：
Campagnolo, E. R.;Moll, M. E.;Ostroff, S. M.
我们报告了2010年秋季在宾夕法尼亚州利哈伊谷地区宠物雪貂中发生的大流行性流感a /H1N1 （pH1N1）感染聚集性病例。这些雪貂与一家宠物店有关。流感聚集发生时，现有的人类监测系统在利哈伊谷的人类中几乎没有发现pH1N1病毒，而且对外来宠物也没有常规的流感监测系统。指示病例是一只2.5个月大的绝育雄性雪貂，因严重流感样疾病（ILI）被送到兽医诊所。为响应流感检测结果呈阳性的实验室通知，并应宾夕法尼亚州卫生部（PADOH）的要求，宾夕法尼亚州农业部（PDA）开展了一项调查，以确定其他患病雪貂，并确定感染的来源和程度。PDA向PADOH通报了雪貂中pH1N1感染的情况，从而加强了对人的监测，并在周围社区发现了pH1N1人感染。发现了另外5只与宠物店有关的感染ILI的雪貂。这次雪貂和人类h1n1流感同时暴发，显示了动物卫生与公共卫生之间的重要联系，并突出了利用兽医诊所对动物和人类之间共有的疾病进行哨点监测的潜力。
We report a fall 2010 cluster of pandemic influenza A/H1N1 (pH1N1) infections in pet ferrets in Lehigh Valley region of Pennsylvania. The ferrets were associated with one pet shop. The influenza cluster occurred during a period when the existing human surveillance systems had identified little to no pH1N1 in humans in the Lehigh Valley, and there were no routine influenza surveillance systems for exotic pets. The index case was a 2.5-month-old neutered male ferret that was presented to a veterinary clinic with severe influenza-like illness (ILI). In response to laboratory notification of a positive influenza test result, and upon request from the Pennsylvania Department of Health (PADOH), the Pennsylvania Department of Agriculture (PDA) conducted an investigation to identify other ill ferrets and to identify the source and extent of infection. PDA notified the PADOH of the pH1N1 infection in the ferrets, leading to enhanced human surveillance and the detection of pH1N1 human infections in the surrounding community. Five additional ferrets with ILI linked to the pet shop were identified. This simultaneous outbreak of ferret and human pH1N1 demonstrates the important link between animal health and public health and highlights the potential use of veterinary clinics for sentinel surveillance of diseases shared between animals and humans.