AGING OF THE HUMAN CRYSTALLINE LENS AND ANTERIOR SEGMENT
AGING OF THE HUMAN CRYSTALLINE LENS AND ANTERIOR SEGMENT
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DOI：
10.1016/0042-6989(94)90266-6
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发表时间：
1994-11-01
期刊：
影响因子：
1.8
通讯作者：
KAUFMAN, PL
中科院分区：
文献类型：
--
作者：
COOK, CA;KORETZ, JF;KAUFMAN, PL
通过Scheimpflg裂隙灯摄影，100名年龄在18-70岁之间的正常正视者的未调节晶状体的变化被表征为受试者年龄的函数。随着年龄的增长，晶状体在矢状面上变厚，但由于角膜到晶状体后表面的距离不变，这表明晶状体质量的中心前移，前房变浅。矢状核厚度与年龄无关，但前皮质厚度和后皮质厚度均随年龄增长而增加，使核和中央沟的位置前移。由数字化图像的归一化和积分透镜密度表示的透镜以高角度散射的光量随着年龄的增加以指数方式增加。与年龄相似的关系在主要的前部不连续区(最大密度)和中央沟(最小密度)观察到。讨论了这些结果与调节和老花眼的关系。
Changes in the unaccommodated human crystalline lens were characterized as a function of subject age for 100 normal emmetropes over the age range 18-70 yr by Scheimpflug slit-lamp photography. With increasing age, the lens becomes thicker sagittally, but since the distance from the cornea to the posterior lens surface remains unchanged, this indicates that the center of lens mass moves anteriorly and the anterior chamber becomes shallower. Sagittal nuclear thickness is independent of age, but both anterior and posterior cortical thicknesses increase with age, shifting the location of the nucleus and the central sulcus in the anterior direction. The amount of light scattered by the lens at high angles, as represented by normalized and integrated lens densities from the digitized images, increases with increasing age in an exponential fashion. Similar relationships to age are observed for the major anterior zone of discontinuity (maximum density) and the central sulcus (minimum density). The relationships of these results to accommodation and presbyopia are discussed.