The Association Between Rate of Initial Weight Loss and Long-Term Success in Obesity Treatment: Does Slow and Steady Win the Race?
The Association Between Rate of Initial Weight Loss and Long-Term Success in Obesity Treatment: Does Slow and Steady Win the Race?
复制标题
DOI：
10.1007/s12529-010-9092-y
复制
发表时间：
2010-09-01
影响因子：
2.7
通讯作者：
Perri, Michael G.
中科院分区：
文献类型：
--
作者：
Nackers, Lisa M.;Ross, Kathryn M.;Perri, Michael G.
关于长期体重管理成功的最佳减肥率存在争议。这项研究调查了逐渐开始的体重减轻是否比快速开始的体重减轻与更大的长期体重减轻有关。分组是从TOURS试验的参与者中抽取的，其中包括中年（平均= 59.3岁）肥胖妇女（平均BMI = 36.8），她们接受了6个月的生活方式干预，随后接受了1年的延长护理计划。研究人员鼓励参与者减少热量摄入，以达到每周减重0.45公斤的目标。根据治疗第一个月的体重减轻率，将各组分为“FAST”（每千日元0.68公斤/周，n = 69）、“MODERATE”（每千日元0.23和< 0.68公斤/周，n = 104）和“SLOW”（< 0.23公斤/周，n = 89）。FAST、MODERATE和SLOW组在6个月时的平均体重变化差异显著（分别为-13.5、-8.9和-5.1 kg, ps < 0.001）， FAST和SLOW组在18个月时的平均体重变化差异显著（分别为-10.9、-7.1和-3.7 kg, ps < 0.001）。6 ~ 18个月体重恢复无显著组间差异（分别为2.6、1.8和1.3 kg, ps < 0.9）。在18个月时，FAST组和MODERATE组实现10%体重减轻的可能性是SLOW组的5.1倍和2.7倍。总的来说，研究结果表明快速减肥对短期和长期都有好处。快速减肥者获得了更大的体重减轻和长期维持，并且不比逐渐减肥者更容易体重反弹。
Controversy exists regarding the optimal rate of weight loss for long-term weight management success.This study examined whether gradual initial weight loss was associated with greater long-term weight reduction than rapid initial loss.Groups were drawn from participants in the TOURS trial, which included a sample of middle-aged (mean = 59.3 years) obese women (mean BMI = 36.8) who received a 6-month lifestyle intervention followed by a 1-year extended care program. Participants were encouraged to reduce caloric intake to achieve weight losses of 0.45 kg/week. Groups were categorized as "FAST" (a parts per thousand yen0.68 kg/week, n = 69), "MODERATE" (a parts per thousand yen0.23 and < 0.68 kg/week, n = 104), and "SLOW" (< 0.23 kg/week, n = 89) based on rate of weight loss during first month of treatment.The FAST, MODERATE, and SLOW groups differed significantly in mean weight changes at 6 months (-13.5, -8.9, and -5.1 kg, respectively, ps < 0.001), and the FAST and SLOW groups differed significantly at 18 months (-10.9, -7.1, and -3.7 kg, respectively, ps < 0.001). No significant group differences were found in weight regain between 6 and 18 months (2.6, 1.8, and 1.3 kg, respectively, ps < 0.9). The FAST and MODERATE groups were 5.1 and 2.7 times more likely to achieve 10% weight losses at 18 months than the SLOW group.Collectively, findings indicate both short- and long-term advantages to fast initial weight loss. Fast weight losers obtained greater weight reduction and long-term maintenance, and were not more susceptible to weight regain than gradual weight losers.