Evidence gaps in economic analyses of hearing healthcare: A systematic review.
Evidence gaps in economic analyses of hearing healthcare: A systematic review.
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DOI：
10.1016/j.eclinm.2021.100872
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发表时间：
2021-05
影响因子：
15.1
通讯作者：
Sanders GD
中科院分区：
文献类型：
--
作者：
Borre ED;Diab MM;Ayer A;Zhang G;Emmett SD;Tucci DL;Wilson BS;Kaalund K;Ogbuoji O;Sanders GD
听力损失是一种常见且昂贵的医疗条件。这项系统性综述旨在确定已发表的基于模型的经济分析中关于听力损失的证据差距，为正在进行的柳叶刀委员会提供模型开发信息。我们检索了截至2020年6月14日的已发表文献，我们的纳入标准包括基于决策模型的成本效益分析，涉及听力损失的诊断、治疗或预防。两名研究者在标题、摘要和全文水平上筛选纳入的文章。对数据进行了提取，并使用先前发表的质量量表对研究的模型结构、数据假设和报告质量进行了评估。在我们检索到的1437篇文章中，117项独特的研究符合纳入标准。这些基于模型的分析大多数在高收入国家进行（n = 96，82%）。评价的干预措施包括听力筛查（n = 35，30%）、人工耳蜗植入（n = 34，29%）、助听器使用（n = 28，24%）、疫苗接种（n = 22，19%）和其他干预措施（n = 29，25%）;一些研究包括多种干预措施。86项研究报告了质量调整或残疾调整生命年的主要结局，其中24项得出了自己的效用值。大多数研究使用决策树（n = 72，62%）或马尔可夫（n = 41，35%）模型。41项研究（35%）纳入了间接经济影响。中位质量评分为92/100（IQR：72-100）。该综述确定了大量文献，探讨了听力保健干预的经济效益。然而，在低收入和中等收入国家评估听力保健以及调查整个生命周期的干预措施方面仍然存在证据差距。此外，围绕听力保健干预的生产力效益以及听力辅助健康状态的实用价值仍然存在相当大的不确定性。未来的经济评估可以解决这些局限性。NCATS 3UL1-TR002553-03S3
Hearing loss is a common and costly medical condition. This systematic review sought to identify evidence gaps in published model-based economic analyses addressing hearing loss to inform model development for an ongoing Lancet Commission. We searched the published literature through 14 June 2020 and our inclusion criteria included decision model-based cost-effectiveness analyses that addressed diagnosis, treatment, or prevention of hearing loss. Two investigators screened articles for inclusion at the title, abstract, and full-text levels. Data were abstracted and the studies were assessed for the qualities of model structure, data assumptions, and reporting using a previously published quality scale. Of 1437 articles identified by our search, 117 unique studies met the inclusion criteria. Most of these model-based analyses were set in high-income countries (n = 96, 82%). The evaluated interventions were hearing screening (n = 35, 30%), cochlear implantation (n = 34, 29%), hearing aid use (n = 28, 24%), vaccination (n = 22, 19%), and other interventions (n = 29, 25%); some studies included multiple interventions. Eighty-six studies reported the main outcome in quality-adjusted or disability-adjusted life-years, 24 of which derived their own utility values. The majority of the studies used decision tree (n = 72, 62%) or Markov (n = 41, 35%) models. Forty-one studies (35%) incorporated indirect economic effects. The median quality rating was 92/100 (IQR:72–100). The review identified a large body of literature exploring the economic efficiency of hearing healthcare interventions. However, gaps in evidence remain in evaluation of hearing healthcare in low- and middle-income countries, as well as in investigating interventions across the lifespan. Additionally, considerable uncertainty remains around productivity benefits of hearing healthcare interventions as well as utility values for hearing-assisted health states. Future economic evaluations could address these limitations. NCATS 3UL1-TR002553-03S3
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影响因子：
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